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本文引用的文献

1
Hypoxia upregulates the expression of PD-L1 via NPM1 in breast cancer.缺氧通过NPM1上调乳腺癌中PD-L1的表达。
J Immunother Cancer. 2025 Jun 23;13(6):e010151. doi: 10.1136/jitc-2024-010151.
2
Nucleophosmin 1 cooperates with the methyltransferase DOT1L to preserve peri-nucleolar heterochromatin organization by regulating H3K27me3 levels and DNA repeats expression.核仁磷酸蛋白 1 通过调节 H3K27me3 水平和 DNA 重复序列的表达,与甲基转移酶 DOT1L 合作,维持核仁周异染色质的组织。
Epigenetics Chromatin. 2023 Sep 28;16(1):36. doi: 10.1186/s13072-023-00511-9.
3
NPM1 upregulates the transcription of PD-L1 and suppresses T cell activity in triple-negative breast cancer.NPM1 上调 PD-L1 的转录并抑制三阴性乳腺癌中的 T 细胞活性。
Nat Commun. 2020 Apr 3;11(1):1669. doi: 10.1038/s41467-020-15364-z.
4
MYC regulates the antitumor immune response through CD47 and PD-L1.MYC 通过 CD47 和程序性死亡受体配体 1(PD-L1)调节抗肿瘤免疫反应。
Science. 2016 Apr 8;352(6282):227-31. doi: 10.1126/science.aac9935. Epub 2016 Mar 10.

Letter to the editor: LSD1 as an upstream epigenetic regulator of NPM1-PD-L1 axis in hypoxia-driven immune evasion in breast cancer.

作者信息

Iqbal Jabed

机构信息

Anatomical Pathology, Singapore General Hospital, Singapore

出版信息

J Immunother Cancer. 2025 Jul 25;13(7):e013071. doi: 10.1136/jitc-2025-013071.

DOI:10.1136/jitc-2025-013071
PMID:40713181
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12306320/
Abstract
摘要