出现一种不与葡聚糖B - 1355s发生反应的MOPC 104E变体。
Appearance of a variant of MOPC 104E which does not react with dextran B-1355s.
作者信息
Folds J D
出版信息
Immunol Commun. 1977;6(4):385-94. doi: 10.3109/08820137709051975.
PMID:407151
Abstract
MOPC 104E is a mouse plasmacytoma which produces an IgM (lambda) myeloma protein. This IgM protein has a binding specificity for dextran B-135s. This report describes a variant of the MOPC 104E tumor which secretes a myeloma protein which does not react with the dextran. The apparent variant of MOPC 104E arose spontaneously during routine passage of the MOPC 104E tumors in Balb/C mice and appears to be stable.
摘要
MOPC 104E是一种小鼠浆细胞瘤，可产生IgM（λ）骨髓瘤蛋白。这种IgM蛋白对葡聚糖B - 135s具有结合特异性。本报告描述了MOPC 104E肿瘤的一种变体，该变体分泌的骨髓瘤蛋白与葡聚糖不发生反应。MOPC 104E的这种明显变体是在MOPC 104E肿瘤在Balb/C小鼠中常规传代过程中自发产生的，并且似乎是稳定的。
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