Qi Chunxia, Mo Biyun, Jiang Changhong, Li Jiali, Bo Xuguang, Xiao Xuhui, Zhou Hao, Long Jun
Department of Laboratory Medicine, ZhuJiang Hospital of Southern Medical University, Guangzhou, Guangdong, 510000, People's Republic of China.
Quality Management Section, ZhuJiang Hospital of Southern Medical University, Guangzhou, Guangdong, 510000, People's Republic of China.
Infect Drug Resist. 2025 Jul 23;18:3671-3675. doi: 10.2147/IDR.S517505. eCollection 2025.
() is a common fungal pathogen that primarily affects plants but can also cause rare infections in humans. In recent years, sporadic cases have been reported worldwide. Here, we report the first case of endophthalmitis in China resulting from a corneal scratch caused by an infected dragon fruit. Exogenous fungal endophthalmitis can be classified into three categories: postoperative, post-traumatic, and keratitis-associated. Currently, there is no standardized antifungal regimen for infections, especially for endophthalmitis, where systemic antibiotics have poor intraocular penetration. Successful management often requires surgical interventions such as amputation or drainage. Our case highlights the diagnostic and therapeutic challenges, as well as the poor outcomes associated with infections in humans.
（）是一种常见的真菌病原体，主要影响植物，但也可导致人类罕见感染。近年来，全球范围内已报告散发病例。在此，我们报告中国首例由受感染火龙果导致角膜擦伤引起的眼内炎病例。外源性真菌性眼内炎可分为三类：术后、创伤后和与角膜炎相关的。目前，对于此类感染，尤其是眼内炎，尚无标准化的抗真菌治疗方案，因为全身用抗生素眼内穿透性差。成功的治疗通常需要手术干预，如截肢或引流。我们的病例突出了诊断和治疗挑战，以及与人类此类感染相关的不良预后。
