Tucker Joshua, Sharma Vidit, Johnson Matthew, Hibbert Rebecca, Kapplinger Jamie, Moynagh Michael, Adamo Daniel, Schmitz John, Parvinian Ahmad
Alix School of Medicine, Mayo Clinic, Rochester, USA.
Department of Urology, Mayo Clinic, Rochester, USA.
Abdom Radiol (NY). 2025 Jul 28. doi: 10.1007/s00261-025-05139-9.
Conventional bladder tumor diagnosis consists of transurethral resections, which are not always feasible and can entail significant morbidity for vulnerable patients. This study was conducted to evaluate the safety and diagnostic yield percutaneous urinary bladder tumor biopsy as an alternative for such cases.
Retrospective review of an institutional database identified 58 patients who underwent 59 bladder tumor biopsies between February 1, 2009 and February 1, 2025. Patient, procedural, and pathologic characteristics were recorded. Adverse events were classified according to Society of Interventional Radiology criteria.
Mean patient age was 68 years (range: 22-90). All procedures were technically successful. Most cases used CT guidance (88.1%) and 17/18 gauge coaxial core biopsy systems (84.7%). Biopsy results were diagnostic in 94.9% of cases. Biopsy results were concordant with surgical pathology in 13/14 (92.9%) patients who subsequently underwent transurethral resection or cystectomy. There were no severe adverse events or procedure-related mortality. There were two minor urinary tract infections following biopsy and two moderate bleeding events requiring treatment.
Percutaneous biopsy is a safe and effective method for sampling urinary bladder tumors.
传统的膀胱肿瘤诊断方法包括经尿道切除术，但这种方法并非总是可行，而且对于脆弱的患者可能会带来显著的发病率。本研究旨在评估经皮膀胱肿瘤活检作为此类病例替代方法的安全性和诊断率。
对一个机构数据库进行回顾性分析，确定了58例在2009年2月1日至2025年2月1日期间接受了59次膀胱肿瘤活检的患者。记录患者、手术和病理特征。根据介入放射学会的标准对不良事件进行分类。
患者平均年龄为68岁（范围：22 - 90岁）。所有手术在技术上均获成功。大多数病例采用CT引导（88.1%）和17/18号同轴芯活检系统（84.7%）。94.9%的病例活检结果具有诊断价值。在随后接受经尿道切除术或膀胱切除术的14例患者中，13例（92.9%）活检结果与手术病理结果一致。没有严重不良事件或与手术相关的死亡。活检后有2例轻微尿路感染和2例需要治疗的中度出血事件。
经皮活检是一种安全有效的膀胱肿瘤取样方法。
