Imbach P
Vox Sang. 1985;49 Suppl 1:25-31. doi: 10.1111/j.1423-0410.1985.tb01140.x.
Since a pilot study of intravenous immune globulin showed it to induce a rapid rise of thrombocytes in immune thrombocytopenia purpura (ITP) in childhood, a randomized study was started for acute, untreated ITP and a prospective study for acute and chronic, pretreated ITP in children. The results of the pilot study and preliminary data of the ongoing studies are presented. Although little is known of the effects of intravenous immune globulin, possible mechanisms of action are discussed.
由于一项静脉注射免疫球蛋白的初步研究表明，它能使儿童免疫性血小板减少性紫癜（ITP）患者的血小板迅速上升，因此针对儿童急性、未经治疗的ITP开展了一项随机研究，并针对急性和慢性、经过预处理的ITP开展了一项前瞻性研究。本文介绍了初步研究的结果以及正在进行的研究的初步数据。尽管人们对静脉注射免疫球蛋白的作用了解甚少，但仍对其可能的作用机制进行了讨论。
