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误诊为黏液瘤的房间隔副神经节瘤:一例报告

Atrial septal paraganglioma mistaken for a myxoma: a case report.

作者信息

Yu Yalu, He Qinze, Xia Jiaqi, Jiang Qin

机构信息

School of Medicine, University of Electronic Science and Technology of China, Chengdu, 610072, Sichuan, China.

Department of Cardiothoracic Surgery, Deyang People's Hospital, Deyang, 618000, Sichuan, China.

出版信息

J Med Case Rep. 2025 Jul 28;19(1):372. doi: 10.1186/s13256-025-05436-3.

Abstract

BACKGROUND

Cardiac tumors are relatively uncommon, with myxoma being the most prevalent. Atrial septal paraganglioma is a significantly rarer form of malignant cardiac tumor that secretes catecholamines. There are notable similarities in their clinical manifestations and imaging characteristics, which can lead to misdiagnosis.

CASE PRESENTATION

We report a case of a 47-year-old Han man with atypical chest pain and syncope who was found to have a mass (3.6 cm × 2.9 cm) in the left atrium. After an imaging examination, a myxoma was suspected. The tumor was excised during a cardiac surgery, and subsequent pathological analysis determined that the mass was actually a paraganglioma. The patient experienced a favorable recovery, and there was no evidence of recurrence during a 1-year period of postoperative monitoring.

CONCLUSION

This case emphasizes the importance of accurate diagnosis of cardiac tumors, especially in atypical clinical manifestations, imaging, and biochemical auxiliary examination. Accurate diagnosis is crucial in the choice of treatment options and prognostic evaluation.

摘要

背景

心脏肿瘤相对少见,其中黏液瘤最为常见。房间隔副神经节瘤是一种极为罕见的分泌儿茶酚胺的恶性心脏肿瘤。它们在临床表现和影像学特征上有显著相似之处,可能导致误诊。

病例报告

我们报告一例47岁汉族男性患者,有非典型胸痛和晕厥症状,经检查发现左心房有一肿块(3.6厘米×2.9厘米)。影像学检查后怀疑为黏液瘤。在心脏手术中切除肿瘤,随后的病理分析确定该肿块实际上是副神经节瘤。患者恢复良好,术后1年的监测期间无复发迹象。

结论

该病例强调了准确诊断心脏肿瘤的重要性,尤其是在非典型临床表现、影像学及生化辅助检查方面。准确诊断对于治疗方案的选择和预后评估至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8732/12306117/c490e8c281df/13256_2025_5436_Fig1_HTML.jpg

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