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子宫微波消融术后手术部位感染的危险因素:一项回顾性队列研究。

Risk factors for surgical site infections following microwave ablation of the uterus: a retrospective cohort study.

作者信息

Chen Chuan, Wu Hanshu, Wang Xinyu, Peng Ying, Peng' Ying, Lei Lei, Zhao Yangyang, Chen Gang

机构信息

Department of Obstetrics and Gynecology, Division of Life Sciences and Medicine, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, 230001, Anhui, China.

China Railway Fourth Bureau Group Central Hospital, Sinopharm Group, Hefei, 230001, Anhui, China.

出版信息

BMC Womens Health. 2025 Jul 28;25(1):375. doi: 10.1186/s12905-025-03810-3.

Abstract

PURPOSE

As microwave ablation (MWA) becomes an increasingly popular treatment for gynecological diseases, complications such as surgical site infections (SSIs) have emerged as critical concerns, particularly in high-risk patient populations. Identifying independent risk factors for SSIs is essential to implement effective preventive measures and enhance patient outcomes.

METHODS

This retrospective study included women aged 18-55 with a diagnosis of uterine myoma or adenomyosis who underwent MWA at the First Affiliated Hospital of the University of Science and Technology of China between December 2020 and November 2023. Patient selection criteria included undergoing laparoscopic MWA by our team and providing written informed consent. The Kolmogorov-Smirnov test was used to assess the normality of continuous variables, and statistical analyses were performed using the Student's t-test, Mann-Whitney U test, and χ2 test. Multivariate logistic regression identified potential predictors for SSIs.

RESULTS

In this study, SSIs were observed in 7.58% of patients, with prolonged surgical duration and abdominal adhesions identified as significant independent risk factors.

CONCLUSION

This study provides insights into SSIs following MWA surgery in a Chinese population, highlighting specific risk factors that could inform preventive strategies to improve surgical outcomes and patient safety.

摘要

目的

随着微波消融(MWA)成为治疗妇科疾病越来越常用的方法,诸如手术部位感染(SSIs)等并发症已成为关键问题,尤其是在高危患者群体中。识别手术部位感染的独立危险因素对于实施有效的预防措施和改善患者预后至关重要。

方法

这项回顾性研究纳入了2020年12月至2023年11月期间在中国科学技术大学附属第一医院接受MWA治疗且年龄在18 - 55岁、诊断为子宫肌瘤或子宫腺肌病的女性患者。患者入选标准包括由我们团队进行腹腔镜MWA治疗并提供书面知情同意书。采用Kolmogorov - Smirnov检验评估连续变量的正态性,并使用Student's t检验、Mann - Whitney U检验和χ2检验进行统计分析。多因素逻辑回归分析确定手术部位感染的潜在预测因素。

结果

在本研究中,7.58%的患者发生了手术部位感染,手术时间延长和腹部粘连被确定为显著的独立危险因素。

结论

本研究为中国人群MWA手术后的手术部位感染提供了见解,突出了特定的危险因素,可为改善手术效果和患者安全的预防策略提供参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f792/12302862/8189cb8caecf/12905_2025_3810_Fig1_HTML.jpg

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