Jamaux Marielle, Gibier Corisande, Dillenseger Laurence, Fourie Gwenaelle, Langlet-Muteau Claire, Rondel Jennifer, Matis Jacqueline, Matz Bénédicte, Schmitt Valérie, Meyer Nicolas, Kuhn Pierre, Zores Claire
Médecine et Réanimation du Nouveau-né, Service de Pédiatrie 2, Pôle Médico-Chirurgical Pédiatrique Hôpital de Hautepierre, Centre Hospitalier Universitaire de Strasbourg, Avenue Molière, 67098 Strasbourg, France.
LNCA, UMR 7364, CNRS and University of Strasbourg, 67081 Strasbourg, France.
Children (Basel). 2025 Jun 26;12(7):840. doi: 10.3390/children12070840.
: Respiratory support required by preterm infants involves contact between their immature skin and ventilation devices, which can lead to skin breakdown. : A prospective observational study including newborns with a nasal injury related to respiratory support, born at gestational age < 33 weeks, from May 2020 to January 2022, in the neonatal intensive care unit of Strasbourg. Injuries were recorded using a validated scale at inclusion and 3, 7 and 28 days. Sequelae were evaluated at discharge and 4, 9 and 12 months post-menstrual age. : In total, 64/276 newborns (23%) had a nasal injury. Most of the injuries were stage 2 (34/64, 53%) and stage 1 (25/64, 39%). The interface most frequently associated with injury was continuous positive airway pressure (53/64, 83%). Favorable evolution was associated with the injury site ( < 0.01) and the type of respiratory support needed when collecting at the 28th day ( = 0.04). At discharge, 34/58 infants (59%) had sequelae. The presence of a scar was associated with the maximum injury severity ( < 0.001) and total duration of respiratory support ( = 0.02). At 12 months, 31/47 infants (66%) had esthetic sequelae. : Nasal injuries related to respiratory support in preterm infants were frequent, and more than half of the injuries resulted in medium-term sequelae.
早产儿所需的呼吸支持涉及他们未成熟的皮肤与通气设备之间的接触，这可能导致皮肤破损。：一项前瞻性观察性研究，纳入了2020年5月至2022年1月在斯特拉斯堡新生儿重症监护病房出生、胎龄<33周且有与呼吸支持相关鼻损伤的新生儿。在纳入时以及第3、7和28天使用经过验证的量表记录损伤情况。在出院时以及月经龄4、9和12个月时评估后遗症情况。：总共64/276名新生儿（23%）有鼻损伤。大多数损伤为2期（34/64，53%）和1期（25/64，39%）。与损伤最常相关的界面是持续气道正压通气（53/64，83%）。良好的转归与损伤部位相关（<0.01）以及在第28天收集时所需的呼吸支持类型相关（=0.04）。出院时，34/58名婴儿（59%）有后遗症。瘢痕的存在与最大损伤严重程度相关（<0.001）以及呼吸支持的总持续时间相关（=0.02）。在12个月时，31/47名婴儿（66%）有美学后遗症。：早产儿与呼吸支持相关的鼻损伤很常见，并且超过一半的损伤导致中期后遗症。
