Song Jae Yen, Kim Kang Seob, Han Chang Hee, Bae Sangrak
Department of Obstetrics and Gynecology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
Department of Urology, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 11765, Republic of Korea.
J Clin Med. 2025 Jul 20;14(14):5145. doi: 10.3390/jcm14145145.
: The objective of this study is to investigate the prevalence and epidemiological changes of major sexually transmitted infections (STIs) in Korea over the past decade. : From 2010 to 2021, patients diagnosed with STIs based on ICD-10 codes were analyzed using Korean Health insurance data. The analysis included the number of patients, prevalence, and age-specific prevalence (in 5-year intervals) over this period. We examined changes in disease patterns over time by analyzing the annual trends and age-specific prevalence of bacterial STIs such as chlamydia, mycoplasma, gonorrhea, and syphilis; viral STIs such as genital herpes, human papillomavirus (HPV), and human immunodeficiency virus (HIV); and other infections including scabies, pubic lice, and trichomoniasis. : In 2010, the STI with the highest prevalence due to an infectious pathogen was trichomoniasis (256.65/100,000), while latent syphilis had the lowest prevalence (5.29/100,000). In 2021, the STI with the highest prevalence was genital herpes (254.54 per 100,000 persons), and latent syphilis continued to have the lowest prevalence. Bacterial STIs showed a decreasing trend. Viral STIs showed a continuous increase throughout the study period, with anogenital warts (AGW) having the highest rate of increase. Other infections showed a decreasing trend. HIV and AGW in men showed a rapid increase. Gender differences varied depending on the disease. : While bacterial STIs have gradually declined, viral STIs have continued to increase during last decade. The characteristics of each pathogen vary according to age and gender, necessitating the establishment of risk groups for each pathogen and the development of prevention policies accordingly.
本研究的目的是调查过去十年韩国主要性传播感染（STIs）的患病率及流行病学变化。从2010年到2021年，利用韩国健康保险数据对根据国际疾病分类第十版（ICD - 10）编码诊断为性传播感染的患者进行分析。分析内容包括这段时期内的患者数量、患病率以及特定年龄组患病率（以5年为间隔）。我们通过分析衣原体、支原体、淋病和梅毒等细菌性性传播感染；生殖器疱疹、人乳头瘤病毒（HPV）和人类免疫缺陷病毒（HIV）等病毒性性传播感染；以及疥疮、阴虱和滴虫病等其他感染的年度趋势和特定年龄组患病率，来研究疾病模式随时间的变化。2010年，由感染病原体导致的患病率最高的性传播感染是滴虫病（256.65/10万），而潜伏梅毒的患病率最低（5.29/10万）。2021年，患病率最高的性传播感染是生殖器疱疹（每10万人中254.54例），潜伏梅毒的患病率仍然最低。细菌性性传播感染呈下降趋势。病毒性性传播感染在整个研究期间持续上升，其中肛门生殖器疣（AGW）的增长率最高。其他感染呈下降趋势。男性中的HIV和AGW呈快速上升趋势。性别差异因疾病而异。虽然细菌性性传播感染在过去十年中逐渐下降，但病毒性性传播感染持续上升。每种病原体的特征因年龄和性别而异，因此有必要针对每种病原体确定风险群体并相应制定预防政策。
