He Haojie, He Jun, Kuai JianKe
Department of Anesthesiology, Xi'an No. 3 Hospital, The Affiliated Hospital of Northwest University, Xi'an, Shaanxi, PR China.
Medicine (Baltimore). 2025 Jul 25;104(30):e43519. doi: 10.1097/MD.0000000000043519.
Posterior reversible encephalopathy syndrome (PRES) is a relatively rare neurological disorder in obstetrics. Clinically, the most common precipitating factors are hypertension, immunosuppressive agents, or chemotherapy drugs. It is extremely rare for PRES to be induced by the entry of local anesthetic into the subdural space.
In this case report, we present an instance where a patient experienced blurred vision, and even blindness, following an accidental subdural block administered by the anesthetist, and was subsequently diagnosed with PRES. The patient was a 30-year-old parturient who developed blurred vision and headache after surgery, which further progressed to blindness.
Based on the clinical manifestations of headache, blurred vision, and even blindness in the patient, in conjunction with the imaging findings of abnormal signals in the bilateral temporal, parietal, and occipital lobes of the brain as well as the cerebellar hemispheres, a diagnosis of PRES was made.
Fluid restriction, diuresis, antihypertensive treatment, and neurotrophic support.
The patient's headache symptoms were rapidly alleviated, and her vision gradually returned to normal, leading to a successful recovery and discharge from the hospital.
This is an extremely unusual case. The accidental subdural block affected the vasoconstriction of the cerebral blood vessels, which induced PRES. Given that postoperative headaches in obstetric patients are often attributed to postdural puncture headache, the initial misdiagnosis and mistreatment by the obstetrician nearly led to a severely adverse prognosis for the patient.
后部可逆性脑病综合征(PRES)在产科中是一种相对罕见的神经系统疾病。临床上,最常见的诱发因素是高血压、免疫抑制剂或化疗药物。局部麻醉药进入硬膜下间隙诱发PRES极为罕见。
在本病例报告中,我们呈现了这样一个案例,一名患者在麻醉师意外实施硬膜下阻滞术后出现视力模糊甚至失明,随后被诊断为PRES。患者为一名30岁的产妇,术后出现视力模糊和头痛,进而发展为失明。
根据患者头痛、视力模糊甚至失明的临床表现,结合脑部双侧颞叶、顶叶和枕叶以及小脑半球异常信号的影像学表现,诊断为PRES。
限制液体摄入、利尿、降压治疗及神经营养支持。
患者头痛症状迅速缓解,视力逐渐恢复正常,康复顺利并出院。
这是一个极其罕见的病例。意外的硬膜下阻滞影响了脑血管的血管收缩,从而诱发了PRES。鉴于产科患者术后头痛常归因于硬膜穿刺后头痛,产科医生最初的误诊和误治险些给患者带来严重不良预后。