Hiasa Y, Kitahori Y, Konishi N, Shimoyama T, Sakaguchi Y, Seki A, Akiyama H, Kose A, Yoshida A
Acta Pathol Jpn. 1985 Jul;35(4):905-14. doi: 10.1111/j.1440-1827.1985.tb00632.x.
An autopsy case of primary systemic amyloidosis with severe cardiac amyloidosis in a 75-year-old Japanese man is reported. The initial signs were dyspnea and cough, followed by general fatigue and loss of appetite. Heart failure, pleural effusion, and liver cysts were found on physiological examination. Autopsy findings were primary systemic amyloidosis with severe diffuse cardiac amyloidosis and cardiac hypertrophy (585 g). Focal necrosis by infarction was found in the liver and spleen. The cause of amyloidosis was unknown.
报告了一例75岁日本男性原发性系统性淀粉样变性伴严重心脏淀粉样变性的尸检病例。最初症状为呼吸困难和咳嗽，随后出现全身乏力和食欲不振。体格检查发现心力衰竭、胸腔积液和肝囊肿。尸检结果为原发性系统性淀粉样变性伴严重弥漫性心脏淀粉样变性和心脏肥大（585克）。肝脏和脾脏发现梗死灶性坏死。淀粉样变性的病因不明。
