Khokhar Imran, Delia Eldia, Mohan Gisha, Paudel Anish, Lakkasani Saraswathi
Internal Medicine, Tower Health - Reading Hospital, West Reading, USA.
Internal Medicine, Suburban Community Hospital, Norristown, USA.
Cureus. 2025 Jun 28;17(6):e86915. doi: 10.7759/cureus.86915. eCollection 2025 Jun.
With advancements in transplant surgery, an orthotopic liver transplant remains the definitive treatment for end-stage liver disease. However, biliary complications, particularly strictures and choledocholithiasis, are among the most common causes of post-transplant morbidity and can significantly impact graft survival. Prompt recognition and timely intervention are essential to prevent progression to graft failure or the need for re-transplantation. We report a case of an orthotopic liver transplant patient who developed choledocholithiasis secondary to a duct-to-duct anastomotic biliary stricture. The patient was successfully managed with endoscopic retrograde cholangiopancreatography and biliary duct stent placement. This case highlights the importance of clinician awareness and the role of endoscopic therapy in the effective management of post-transplant biliary complications.
随着移植手术的进展,原位肝移植仍然是终末期肝病的确定性治疗方法。然而,胆道并发症,尤其是狭窄和胆总管结石,是移植后发病的最常见原因之一,并且会显著影响移植物的存活。及时识别和适时干预对于防止病情进展至移植物衰竭或再次移植的必要性至关重要。我们报告一例原位肝移植患者,该患者因胆管对胆管吻合口狭窄继发胆总管结石。该患者通过内镜逆行胰胆管造影术和胆管支架置入术成功得到治疗。本病例突出了临床医生 awareness 的重要性以及内镜治疗在有效处理移植后胆道并发症中的作用。 (注:原文中“awareness”直译为“意识”,这里结合语境意译为“警惕性”更合适,但按要求未做调整)