Blomstrand E, Larsson L, Edström L
Acta Physiol Scand. 1985 Oct;125(2):235-43. doi: 10.1111/j.1748-1716.1985.tb07712.x.
The influence of muscle temperature (28 and 36 degrees C) on fatiguability and glycolytic metabolism was studied during 5 min of intermittent stimulation of motor nerves of the tibialis anterior, extensor digitorum longus (fast-twitch) and soleus (slow-twitch) muscles in the rat at 100 Hz (200 ms per s). The decline in isometric tension was not affected by muscle temperature either in fast- or in slow-twitch muscles. In fast-twitch muscles the utilization of glycogen during stimulation was the same at 28 and 36 degrees C, while in the soleus muscle it was lower at 28 degrees C. The concentration of glucose-6-phosphate immediately after stimulation was higher in the muscles at 28 degrees C than in those at 36 degrees C, whereas no difference in lactate concentration was found between the two temperature groups. These observations indicate that compared with the rate at 36 degrees C, the rate of glycogenolysis at 28 degrees C is unchanged in fast-twitch, but decreased in slow-twitch muscle. This might imply increased economy of ATP turnover during contraction in the soleus muscle at 28 degrees C.
在100Hz（每秒200毫秒）的频率下，对大鼠的胫前肌、趾长伸肌（快肌纤维）和比目鱼肌（慢肌纤维）的运动神经进行5分钟的间歇性刺激，研究了肌肉温度（28摄氏度和36摄氏度）对疲劳性和糖酵解代谢的影响。无论是快肌纤维还是慢肌纤维，等长张力的下降都不受肌肉温度的影响。在快肌纤维中，28摄氏度和36摄氏度时刺激期间糖原的利用率相同，而在比目鱼肌中，28摄氏度时的糖原利用率较低。刺激后即刻，28摄氏度肌肉中葡萄糖-6-磷酸的浓度高于36摄氏度肌肉中的浓度，而两个温度组之间乳酸浓度没有差异。这些观察结果表明，与36摄氏度时相比，28摄氏度时快肌纤维中糖原分解速率不变，但慢肌纤维中糖原分解速率降低。这可能意味着28摄氏度时比目鱼肌收缩过程中ATP周转的经济性增加。
