Hu Xiexin, Xu Jing, Wang Kang
College of Bioscience and Biotechnology, Yangzhou University, Yangzhou 225009, China.
College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Curr Issues Mol Biol. 2025 Jul 17;47(7):554. doi: 10.3390/cimb47070554.
Epigenetics, as an important scientific field that bridges genomic function and phenotypic plasticity, increasingly demonstrates its value in bee research. In recent years, with the rapid development of omics technologies, there have been significant advancements in the study of epigenetics in honeybees. This article reviews the role of epigenetic regulation in the development, behavioral regulation, and immune response of honeybee larvae from the perspectives of DNA methylation, histone modification, and non-coding RNA. With the continuous deepening of related research, honeybee epigenetics not only opens new paths for understanding the formation mechanisms of complex traits in social insects but also provides solid theoretical support and innovative perspectives for the study of social insects and beekeeping practices. These insights also inform sustainable beekeeping practices.
表观遗传学作为连接基因组功能和表型可塑性的重要科学领域，在蜜蜂研究中日益彰显其价值。近年来，随着组学技术的飞速发展，蜜蜂表观遗传学研究取得了重大进展。本文从DNA甲基化、组蛋白修饰和非编码RNA的角度综述了表观遗传调控在蜜蜂幼虫发育、行为调控和免疫反应中的作用。随着相关研究的不断深入，蜜蜂表观遗传学不仅为理解社会性昆虫复杂性状的形成机制开辟了新途径，也为社会性昆虫研究和养蜂实践提供了坚实的理论支持和创新视角。这些见解也为可持续养蜂实践提供了参考。
