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Effect of butorphanol tartrate on food and water consumption in humans.

作者信息

Morley J E, Parker S, Levine A S

出版信息

Am J Clin Nutr. 1985 Dec;42(6):1175-8. doi: 10.1093/ajcn/42.6.1175.

DOI:10.1093/ajcn/42.6.1175
PMID:4072953
Abstract

There is much evidence that endogenous opioid peptides are involved in the regulation of food and water intake in a variety of species. We report here that the exogenous opiate agonist, butorphanol tartrate (1 microgram/kg), significantly increases food, but not water, intake in normal humans. The major effect on food intake was seen within the first 2 h after the administration of drug. These findings suggest that this drug may be therapeutically useful in patients with cancer anorexia.

摘要

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