McCallum Gregory E, Hall James P J
Department of Evolution, Ecology and Behaviour, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.
NPJ Antimicrob Resist. 2025 Jul 29;3(1):68. doi: 10.1038/s44259-025-00137-9.
The hospital sink drain microbiome can harbour opportunistic pathogens and antimicrobial resistance genes (ARGs). Aspects of this habitat, such as exposure to disinfectants, antibiotics, nutrients, and body fluids could exacerbate horizontal gene transfer of ARGs and clinically impactful pathogen resistance. Here, we explore features of the hospital sink drain that may favour ARG acquisition and transmission, highlight studies providing evidence of transfer, and consider strategies to mitigate these risks.
医院水槽排水口微生物群可能携带机会性病原体和抗菌抗性基因（ARGs）。该栖息地的一些因素，如接触消毒剂、抗生素、营养物质和体液，可能会加剧ARGs的水平基因转移，并对临床上有影响的病原体抗性产生影响。在此，我们探讨医院水槽排水口可能有利于ARGs获取和传播的特征，强调提供转移证据的研究，并考虑降低这些风险的策略。
