Seitchik J, Holden A E, Castillo M
Am J Obstet Gynecol. 1985 Dec 15;153(8):848-54. doi: 10.1016/0002-9378(85)90688-x.
A group of 242 nulliparous women in spontaneous, term, first-stage, true labor, with cephalic presentations and intact membranes, underwent amniotomy in the first stage. Sixty-nine of 242 (29%) received oxytocin prior to complete dilatation. The group that received oxytocin was characterized by fewer women less than 20 years of age, more patients with an additional diagnosis such as preeclampsia, longer labors, and slower mean rates of dilatation before and after amniotomy. There was no correlation between the last dilatation rate before and the first after amniotomy. The only significant predictors of oxytocin use were cervical dilatation at amniotomy and the first rate of dilatation afterward. Of patients with dilatation at a rate of greater than or equal to 1 cm/hr from admission to amniotomy, 16% received oxytocin; if less than 1 cm/hr, 39%. Two different rate standards were used to differentiate "unsatisfactory" from "satisfactory" labor: (1) less than 1 or greater than or equal to 1 cm/hr and (2) no change or some change in dilatation. Neither of these standards, when applied to the first examination after amniotomy, predicts patients who will receive oxytocin with any reasonable degree of efficiency. Examination of cervical dilatation after amniotomy in patients who did not receive oxytocin demonstrated failure of the cervix to dilate in approximately 20% of each of three sequential examinations. Contrariwise, no dilatation for 2 hours was uncommon. Amniotomy appears to enhance the dilatation rate in patients with well-dilated cervices that are already dilating at a satisfactory rate and slows dilatation in some patients, particularly those with cervices that are less dilated. These results suggest that amniotomy should be performed for specific indications only.
一组242名未生育过的妇女,处于足月、第一产程、自然发动的真性分娩,头先露且胎膜完整,在第一产程接受了人工破膜。242名妇女中有69名(29%)在宫口完全扩张前接受了缩宫素治疗。接受缩宫素治疗的组具有以下特点:年龄小于20岁的女性较少,更多患者有子痫前期等附加诊断,产程较长,人工破膜前后平均扩张速度较慢。人工破膜前最后一次扩张速度与破膜后第一次扩张速度之间无相关性。使用缩宫素的唯一显著预测因素是人工破膜时的宫颈扩张程度及之后的首次扩张速度。从入院到人工破膜时扩张速度大于或等于1厘米/小时的患者中,16%接受了缩宫素治疗;如果扩张速度小于1厘米/小时,则为39%。采用两种不同的速度标准来区分“不满意”和“满意”的产程:(1)小于1或大于或等于1厘米/小时,以及(2)扩张无变化或有一些变化。当将这些标准应用于人工破膜后的首次检查时,均无法以任何合理的效率预测哪些患者会接受缩宫素治疗。对未接受缩宫素治疗的患者进行人工破膜后宫颈扩张检查发现,在连续三次检查中,每次约20%的患者宫颈未扩张。相反,2小时未扩张并不常见。人工破膜似乎能提高宫颈扩张良好且已以满意速度扩张的患者的扩张速度,并使一些患者,特别是宫颈扩张较小的患者的扩张速度减慢。这些结果表明,人工破膜应仅用于特定指征。