Sule Ashita Ashish, Sah Shreya, Kwan Justin, Punamiya Sundeep, Shelat Vishal G
Yong Loo Lin School of Medicine, National University of Singapore, 10 Medical Drive, Singapore 117597, Singapore.
Department of Medicine, University of New South Wales Sydney, Kensington, Sydney, NSW 2033, Australia.
Medicina (Kaunas). 2025 Jul 21;61(7):1312. doi: 10.3390/medicina61071312.
: Visceral arterial pseudoaneurysms (VAPAs) are rare vascular lesions characterized by the disruption of partial disruption of the arterial wall, most commonly involving the intima and media. They have an estimated incidence of 0.1-0.2%, with the splenic artery most commonly affected. Their management poses unique challenges due to the high risk of rupture. Timely recognition is crucial, as unmanaged pseudoaneurysms have a mortality rate of 90%. This narrative review aims to synthesize current knowledge regarding the epidemiology, etiology, clinical presentation, diagnostic methods, and management strategies for VAPAs. : A literature search was performed across Pubmed for articles reporting on VAPAs, including case reports, review articles, and cohort studies, with inclusion of manuscripts that were up to (date). VAPAs are grouped by embryological origin-foregut, midgut, and hindgut. : Chronic pancreatitis is a primary cause of VAPAs, with the splenic artery being involved in 60-65% of cases. Other causes include acute pancreatitis, as well as iatrogenic trauma from surgeries, trauma, infections, drug use, and vascular diseases. VAPAs often present as abdominal pain upon rupture, with symptoms like nausea, vomiting, and gastrointestinal hemorrhage. Unruptured pseudoaneurysms may manifest as pulsatile masses or bruits but are frequently asymptomatic and discovered incidentally. Diagnosis relies on both non-invasive imaging techniques, such as CT angiography and Doppler ultrasound, and invasive methods like digital subtraction angiography, which remains the gold standard for detailed evaluation and treatment. A range of management options exists that are tailored to individual cases based on the aneurysm's characteristics and patient-specific factors. This encompasses both surgical and endovascular approaches, with a growing preference for minimally invasive techniques due to lower associated morbidity. : VAPAs are a critical condition requiring prompt early recognition and intervention. This review highlights the need for ongoing research to improve diagnostic accuracy and refine treatment protocols, enhancing patient outcomes in this challenging domain of vascular surgery.
内脏动脉假性动脉瘤(VAPAs)是一种罕见的血管病变,其特征是动脉壁部分破裂,最常累及内膜和中膜。据估计,其发病率为0.1%-0.2%,最常受累的是脾动脉。由于破裂风险高,其治疗带来了独特的挑战。及时识别至关重要,因为未治疗的假性动脉瘤死亡率达90%。本叙述性综述旨在综合目前关于VAPAs的流行病学、病因、临床表现、诊断方法和治疗策略的知识。在PubMed上进行了文献检索,以查找关于VAPAs的文章,包括病例报告、综述文章和队列研究,纳入截至(日期)的手稿。VAPAs按胚胎起源分为前肠、中肠和后肠。慢性胰腺炎是VAPAs的主要原因,60%-65%的病例累及脾动脉。其他原因包括急性胰腺炎,以及手术、外伤、感染、药物使用和血管疾病引起的医源性创伤。VAPAs破裂时通常表现为腹痛,伴有恶心、呕吐和胃肠道出血等症状。未破裂的假性动脉瘤可能表现为搏动性肿块或血管杂音,但通常无症状,多为偶然发现。诊断依赖于非侵入性成像技术,如CT血管造影和多普勒超声,以及侵入性方法,如数字减影血管造影,后者仍是详细评估和治疗的金标准。根据动脉瘤的特征和患者的具体因素,有一系列针对个体病例的治疗选择。这包括手术和血管内治疗方法,由于相关发病率较低且越来越倾向于微创技术。VAPAs是一种危急情况,需要早期迅速识别和干预。本综述强调了持续研究的必要性,以提高诊断准确性和完善治疗方案,改善血管外科这一具有挑战性领域的患者预后。