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用于医学内窥镜成像系统的红外广角超构透镜设计

Design of an infrared wide-angle metalens for medical endoscopic imaging systems.

作者信息

Zhao Xinjie, Peng Xing, Xu Shaohui, Li Shiqing, Cao Hongbing, Shi Feng

出版信息

Opt Express. 2025 Jul 14;33(14):29182-29196. doi: 10.1364/OE.567336.

Abstract

With the development of minimally invasive diagnostic and therapeutic techniques, medical endoscopes face challenges in achieving synergistic optimization of miniaturization, wide field of view (FOV), and high resolution within narrow anatomical environments such as the digestive tract and blood vessels. Traditional refractive lens systems are limited by volume expansion, aberration accumulation, and packaging complexity, making it difficult to meet the precise imaging requirements in complex anatomical scenarios. This paper proposes an innovative design for a single-wavelength near-infrared wide-field metalens based on a doublet metalens architecture. By optimizing the phase distribution of cascaded metasurfaces and the design of nanostructures, the system achieves a ± 50° FOV at a wavelength of 1.5 μm. The system features an aperture of 1.8 mm, relative illuminance > 98.89%, Strehl Ratio > 0.995, and a modulation transfer function (MTF) close to the diffraction limit, exceeding 0.84 at 21 lp/mm. Simulation results show that through the collaborative effect of the corrector plate and focusing metasurface, the doublet metalens maintains a full width at half maximum (FWHM) of 6.212 micrometers and low sidelobe intensity < 1.74% even at the extreme 50° FOV. This study effectively overcomes the field of view-aberration contradiction of single-layer metalenses through the synergistic effect of wavefront pre-compensation and main focusing, significantly enhancing the nanoscale characterization capability of vascular wall microstructures. It provides an innovative solution for miniaturization and high-resolution imaging of medical narrow-bandwidth endoscopes, remarkably strengthening the ability to characterize vascular wall microstructures and demonstrating important clinical application potential.

摘要

随着微创诊断和治疗技术的发展,医用内窥镜在诸如消化道和血管等狭窄解剖环境中实现小型化、宽视野(FOV)和高分辨率的协同优化上面临挑战。传统的折射透镜系统受到体积膨胀、像差累积和封装复杂性的限制,难以满足复杂解剖场景下的精确成像要求。本文提出了一种基于双合金属透镜结构的单波长近红外宽视野金属透镜的创新设计。通过优化级联超表面的相位分布和纳米结构设计,该系统在1.5μm波长处实现了±50°的视野。该系统孔径为1.8mm,相对照度>98.89%,斯特列尔比>0.995,调制传递函数(MTF)接近衍射极限,在21lp/mm处超过0.84。仿真结果表明,通过校正板和聚焦超表面的协同作用,即使在50°的极端视野下,双合金属透镜仍保持6.212微米的半高全宽(FWHM)和<1.74%的低旁瓣强度。本研究通过波前预补偿和主聚焦的协同作用有效克服了单层金属透镜的视野-像差矛盾,显著增强了血管壁微观结构的纳米级表征能力。它为医用窄带内窥镜的小型化和高分辨率成像提供了一种创新解决方案,显著增强了表征血管壁微观结构的能力,并展示了重要的临床应用潜力。

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