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与接受髂内动脉结扎术的围产期子宫切除术患者相比,原发性围产期子宫切除术治疗产后大出血失败的结局。

Outcomes in failed Primary Peripartum Hysterectomy for massive postpartum heamorrhage as compared to patients undergoing Peripartum Hysterectomy with internal iliac artery ligation.

作者信息

Zahoor Farnaz, Abrar Saida, Hamid Syed Muhammad

机构信息

Farnaz Zahoor, FCPS, CHPE, CHR, Department of OBGYN, MTI Lady Reading Hospital, Peshawar KPK, Pakistan.

Saida Abrar, FCPS Fellowship Urogynaecology and Pelvic Reconstructive Surgery, CHR, Department of OBGYN, MTI Lady Reading Hospital, Peshawar KPK, Pakistan.

出版信息

Pak J Med Sci. 2025 Jul;41(7):1974-1979. doi: 10.12669/pjms.41.7.8174.

DOI:10.12669/pjms.41.7.8174
PMID:40735591
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12302101/
Abstract

OBJECTIVE

To evaluate the outcomes in patients undergoing peripartum hysterectomy alone for massive primary postpartum haemorrhage (Peri-hyst) compared to a patient undergoing Emergency peripartum hysterectomy with bilateral internal iliac artery ligation. (Peri-hyst + BIIAL).

METHODS

It was a cross-sectional comparative study conducted over two years from April 2021 to March 2023, conducted in OBGYN department of Lady Reading Hospital, Peshawar, KPK. The primary outcome was the failure of primary procedure in both group to control blood loss and required relaparotomy. Group-1 were patients undergoing pripartum hysterectomy alone and was compared with Group-2 of the patient in whom bilateral internal iliac artery ligation was also carried out at the time of Peripartum hysterectomy (Peri-hyst +BIAAL). Secondary outcomes analyzed were complications like damage to structure like ureters or sigmoid colon, internal iliac vein injury and haematoma formation in both procedures.

RESULTS

When we compare the mean outcomes of both groups by t test, it is seen that group-I had more ICU admission 15(57.7%) verses 11(42.3%), more maternal morbidity in ICU and more maternal deaths Five (55.6%) versus 4(44.4%) massive heamorrhage 25(65.8%)versus 13(34.2%), acute renal failure, acute respiratory failure p=0.818.

CONCLUSION

Failed primary surgical management to control haemorrhage without BIIAL leads to grave outcomes as seen in most admission in ICU and maternal deaths. Early resort to IIAL is vital for improving the patient outcome when they present with massive haemorrhage.

摘要

目的

评估单纯行围产期子宫切除术治疗大量原发性产后出血(围产期子宫切除术组)与行急诊围产期子宫切除术并双侧髂内动脉结扎术(围产期子宫切除术+双侧髂内动脉结扎术组)患者的结局。

方法

这是一项横断面比较研究,于2021年4月至2023年3月的两年内在开伯尔-普赫图赫瓦省白沙瓦市雷丁夫人医院妇产科进行。主要结局是两组中初次手术未能控制出血且需要再次剖腹手术的情况。第1组为单纯行产前子宫切除术的患者,并与第2组进行比较,第2组患者在围产期子宫切除术时还进行了双侧髂内动脉结扎术(围产期子宫切除术+双侧髂内动脉结扎术)。分析的次要结局是两种手术中的并发症,如输尿管或乙状结肠等结构损伤、髂内静脉损伤和血肿形成。

结果

当我们通过t检验比较两组的平均结局时,发现第1组有更多患者入住重症监护病房,分别为15例(57.7%)和11例(42.3%),在重症监护病房的产妇发病率更高,产妇死亡更多,分别为5例(55.6%)和4例(44.4%),大出血分别为25例(65.8%)和13例(34.2%),急性肾衰竭、急性呼吸衰竭,p = 0.818。

结论

如在大多数重症监护病房入院病例和产妇死亡病例中所见,在未行双侧髂内动脉结扎术的情况下,初次手术未能控制出血会导致严重后果。当患者出现大量出血时,早期采用双侧髂内动脉结扎术对于改善患者结局至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67c6/12302101/389d6083acdb/PJMS-41-1974-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67c6/12302101/389d6083acdb/PJMS-41-1974-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67c6/12302101/389d6083acdb/PJMS-41-1974-g001.jpg

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Outcomes in failed Primary Peripartum Hysterectomy for massive postpartum heamorrhage as compared to patients undergoing Peripartum Hysterectomy with internal iliac artery ligation.与接受髂内动脉结扎术的围产期子宫切除术患者相比,原发性围产期子宫切除术治疗产后大出血失败的结局。
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本文引用的文献

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Incidence, Indications, Risk Factors, and Outcomes of Emergency Peripartum Hysterectomy Worldwide: A Systematic Review and Meta-analysis.全球紧急围产期子宫切除术的发病率、适应症、危险因素及结局:一项系统评价和荟萃分析
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Uterine atony.子宫乏力。
Curr Opin Obstet Gynecol. 2022 Apr 1;34(2):82-89. doi: 10.1097/GCO.0000000000000776.
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The effect of surgical procedure on surgical outcomes in patients undergoing emergency peripartum hysterectomy: a retrospective multicenter study.
手术方式对接受紧急围生期子宫切除术患者手术结局的影响:一项回顾性多中心研究。
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Acta Obstet Gynecol Scand. 2020 Oct;99(10):1364-1373. doi: 10.1111/aogs.13892. Epub 2020 May 21.
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Epidemiology, prevention and management of early postpartum hemorrhage - a systematic review.产后早期出血的流行病学、预防与管理——一项系统综述
Ginekol Pol. 2020;91(1):38-44. doi: 10.5603/GP.2020.0009.
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Small invasive technique of Internal Iliac Artery ligation for postpartum haemorrhage.髂内动脉结扎术治疗产后出血的小切口微创技术
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A Marked Increase in Obstetric Hysterectomy for Placenta Accreta.胎盘植入导致的产科子宫切除术显著增加。
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