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复杂大动脉转位手术的进展:聚焦主动脉根部移位术

Update on Surgery for Complex Transposition of the Great Arteries: Focusing on Aortic Root Translocation.

作者信息

Lee Chang-Ha

机构信息

Department of Thoracic and Cardiovascular Surgery, Bucheon Sejong Hospital, Bucheon, Korea.

出版信息

Korean Circ J. 2025 Jun 27. doi: 10.4070/kcj.2025.0164.

DOI:10.4070/kcj.2025.0164
PMID:40736384
Abstract

Transposition of the great arteries (TGA) is a congenital heart defect (CHD) characterized by discordance between the ventricles and great arteries. The arterial switch operation generally provides excellent early and long-term outcomes in cases in which both great arteries are well developed. Furthermore, various surgical techniques, including the Rastelli procedure, réparation à l'étage ventriculaire (REV) procedure, and pulmonary root translocation have been introduced to improve the outcomes in patients with complex TGA accompanied by significant left ventricular (LV) outflow tract obstruction. A common feature of these 3 techniques is the intraventricular tunneling of the LV to the aorta through the ventricular septal defect while maintaining the original position of the aortic root. Recently, aortic root translocation (ART), which reconstructs the biventricular outflow tracts by repositioning the aortic root toward the pulmonary side, has been reevaluated as an alternative to conventional techniques. Early experiences with ART have reported technical challenges, in addition to high surgical mortality and morbidity rates. Nevertheless, with an increase in surgical experience, early outcomes comparable to those of non-ART procedures have been reported, along with improved long-term results. A key principle of ART is to preserve the integrity of the aortic root geometry. Various modifications have been introduced to achieve this. As a potential solution, we propose an aortic root reconstruction technique, which we briefly introduce here. Furthermore, ART has been applied in patients with complex congenitally corrected TGA, and we anticipate that this technique will facilitate safer and more feasible biventricular repair in patients with complex CHDs.

摘要

大动脉转位(TGA)是一种先天性心脏病(CHD),其特征是心室与大动脉之间不一致。在两条大动脉发育良好的情况下,动脉调转手术通常能带来出色的早期和长期效果。此外,还引入了各种手术技术,包括Rastelli手术、心室水平修复(REV)手术和肺动脉根部移位术,以改善伴有严重左心室(LV)流出道梗阻的复杂TGA患者的治疗效果。这三种技术的一个共同特点是通过室间隔缺损将左心室在心室内隧道连接至主动脉,同时保持主动脉根部的原始位置。最近,主动脉根部移位术(ART),即将主动脉根部向肺动脉侧重新定位以重建双心室流出道,已作为传统技术的替代方法被重新评估。ART的早期经验除了报告手术死亡率和发病率高之外,还存在技术挑战。然而,随着手术经验的增加,已报告其早期效果与非ART手术相当,长期结果也有所改善。ART的一个关键原则是保持主动脉根部几何形状的完整性。为此引入了各种改良方法。作为一种潜在的解决方案,我们提出一种主动脉根部重建技术,在此简要介绍。此外,ART已应用于复杂的先天性矫正型TGA患者,我们预计该技术将有助于更安全、更可行地修复复杂CHD患者的双心室。

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