Fine-tuning ILC2s: CD48 Pumps Up the Volume.
作者信息
Huang Yung-An, Doherty Taylor A
机构信息
University of California San Diego, Medicine, La Jolla, California, United States.
US Department of Veterans Affairs, Washington, District of Columbia, United States.
出版信息
Am J Respir Cell Mol Biol. 2025 Jul 30. doi: 10.1165/rcmb.2025-0381ED.
Abstract
摘要
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本文引用的文献
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Targeting CD48 Ameliorates ILC2-mediated Airway Hyperreactivity by Disrupting the PKCβ Pathway.靶向CD48通过破坏PKCβ信号通路改善ILC2介导的气道高反应性。
Am J Respir Cell Mol Biol. 2025 Jul 28. doi: 10.1165/rcmb.2025-0299OC.
2
Blocking CD226 regulates type 2 innate lymphoid cell effector function and alleviates airway hyperreactivity.阻断 CD226 调节 2 型固有淋巴细胞的效应功能并减轻气道高反应性。
J Allergy Clin Immunol. 2024 May;153(5):1406-1422.e6. doi: 10.1016/j.jaci.2024.01.003. Epub 2024 Jan 19.
3
The Role of Type 2 Innate Lymphoid Cells in Allergic Diseases.2 型固有淋巴细胞在过敏性疾病中的作用。
Front Immunol. 2021 Jun 9;12:586078. doi: 10.3389/fimmu.2021.586078. eCollection 2021.
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TNFR2 Signaling Enhances ILC2 Survival, Function, and Induction of Airway Hyperreactivity.TNFR2 信号增强了 ILC2 的存活、功能，并诱导了气道高反应性。
Cell Rep. 2019 Dec 24;29(13):4509-4524.e5. doi: 10.1016/j.celrep.2019.11.102.
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ICAM-1 controls development and function of ILC2.ICAM-1 控制 ILC2 的发育和功能。
J Exp Med. 2018 Aug 6;215(8):2157-2174. doi: 10.1084/jem.20172359. Epub 2018 Jul 26.
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Tissue-Restricted Adaptive Type 2 Immunity Is Orchestrated by Expression of the Costimulatory Molecule OX40L on Group 2 Innate Lymphoid Cells.组织受限适应性 2 型免疫是由 2 型先天淋巴细胞表达共刺激分子 OX40L 来协调的。
Immunity. 2018 Jun 19;48(6):1195-1207.e6. doi: 10.1016/j.immuni.2018.05.003. Epub 2018 Jun 12.
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Lipid regulation of group 2 innate lymphoid cell function: Moving beyond epithelial cytokines.2型固有淋巴细胞功能的脂质调节：超越上皮细胞因子
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