Foit F F, Cowell R L, Brobst D F, Moore M P, Tarr B D
Am J Vet Res. 1985 Nov;46(11):2404-8.
Most of the urinary crystals in 2 dogs intoxicated with ethylene glycol had prismatic (rod-like, hippurate-like), and to a less extent, hemp seed or spindle shapes. Using X-ray powder diffraction and optical analysis, these crystals were identified as calcium oxalate monohydrate. A few crystals of calcium oxalate dihydrate (envelope shape) were also observed in the urine sediment. Their presence was confirmed by the appearance of weak X-ray peaks having interplanar spacings ranging from 0.617 to 0.620 nm, which are thought to correspond to the 200 X-ray reflection of calcium oxalate dihydrate. Thus, the 6-sided hippurate-like crystals in the urine of ethylene glycol-poisoned dogs are actually calcium oxalate monohydrate.
