[肌酸磷酸激酶（CPK）、乳酸脱氢酶（LDH）及其同工酶在检测杜氏型肌营养不良携带者中的比较研究]
[Comparative study between CPK, LDH and their isoenzymes in the detection of carriers of Duchenne's type muscular dystrophy].
作者信息
Castro-Gago M, Rodríguez-Segade S, Paz M, Novo I, Pombo M, Tojo R
出版信息
An Esp Pediatr. 1985 Sep;23(3):170-4.
Results of a comparative study of serum activity levels of creatine kinase, lactodehydrogenase and their isoenzyme in mothers of 13 children with Duchenne progressive muscular distrophy are presented. CPK sensibility was 100%, while that of LDH1/LDH2 and LDH5 were 23% and 38,4% respectively. It is concluded that CPK has a great liability index, and that it is superior to LDT and their isoenzyme for detection of carriers of Duchenne progressive muscular distrophy.
本文呈现了对13名患有杜兴氏进行性肌营养不良症患儿母亲的血清肌酸激酶、乳酸脱氢酶及其同工酶活性水平的比较研究结果。肌酸磷酸激酶（CPK）敏感性为100%，而乳酸脱氢酶1/乳酸脱氢酶2（LDH1/LDH2）和乳酸脱氢酶5（LDH5）的敏感性分别为23%和38.4%。结论是CPK具有很高的诊断指数，在检测杜兴氏进行性肌营养不良症携带者方面优于乳酸脱氢酶（LDT）及其同工酶。
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