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唾液中孕酮的直接检测:与血清直接检测的比较

Direct assay for progesterone in saliva: comparison with a direct serum assay.

作者信息

Webley G E, Edwards R

出版信息

Ann Clin Biochem. 1985 Nov;22 ( Pt 6):579-85. doi: 10.1177/000456328502200605.

DOI:10.1177/000456328502200605
PMID:4073790
Abstract

Direct assays have been described for the estimation of progesterone in serum and saliva. Both methods showed good inter-assay precision over a year, and the serum assay is now being used routinely in clinical laboratories. A highly significant correlation was obtained for progesterone concentrations in matched serum and saliva samples over a wide range of concentrations. The concentrations of progesterone in daily samples taken through the menstrual cycle fell within the range quoted in previous studies. The benefits of direct saliva measurement are described with reference to the long-term assessment of irregular cycles. Care in sample collection is necessary since contamination with agents such as oral cosmetics may result in overestimation of progesterone concentrations.

摘要

已经描述了用于估计血清和唾液中孕酮的直接检测方法。两种方法在一年中均显示出良好的批间精密度,并且血清检测目前正在临床实验室中常规使用。在很宽的浓度范围内,匹配的血清和唾液样本中的孕酮浓度获得了高度显著的相关性。在月经周期中采集的日常样本中的孕酮浓度落在先前研究引用的范围内。参照不规则周期的长期评估描述了直接唾液测量的益处。由于诸如口腔化妆品等物质的污染可能导致孕酮浓度的高估,因此样本采集时需要小心。

相似文献

1
Direct assay for progesterone in saliva: comparison with a direct serum assay.唾液中孕酮的直接检测:与血清直接检测的比较
Ann Clin Biochem. 1985 Nov;22 ( Pt 6):579-85. doi: 10.1177/000456328502200605.
2
Radioimmunoassay of progesterone in saliva: application to the assessment of ovarian function.唾液中孕酮的放射免疫测定:在卵巢功能评估中的应用。
Clin Chem. 1979 Dec;25(12):2030-3.
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Radioimmunoassay of progesterone in saliva.
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A simple, direct radioimmunoassay for salivary progesterone determination during the menstrual cycle.一种用于测定月经周期中唾液孕酮的简单、直接的放射免疫分析方法。
Clin Chem. 1986 Jun;32(6):948-51.
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Radioimmunoassay for progesterone in human saliva during the menstrual cycle.
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Comparison of blood spot, salivary and serum progesterone assays in the normal menstrual cycle.正常月经周期中血斑、唾液和血清孕酮检测的比较。
Clin Endocrinol (Oxf). 1986 Jan;24(1):31-8. doi: 10.1111/j.1365-2265.1986.tb03251.x.
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Radioimmunoassay of plasma and salivary progesterone during the menstrual cycle.
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Radioimmunoassay of progesterone in saliva: a simplified technique using 125I-radioligand.唾液中孕酮的放射免疫测定:一种使用¹²⁵I放射性配体的简化技术。
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An improved measurement of progesterone in saliva and clinical applications.唾液中孕酮的改良检测方法及其临床应用。
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