Cooper J D, Turnell D C, Pilcher J, Lockhart D
Ann Clin Biochem. 1985 Nov;22 ( Pt 6):614-7. doi: 10.1177/000456328502200611.
Patients taking oral doses of perhexiline maleate have been examined. Measurement of serum perhexiline concentrations established that different dose requirements between patients were necessary due to the different doses at which drug saturation was achieved. Measurement of serum perhexiline concentrations are essential if side-effects from the drug are to be avoided.
对服用马来酸哌克昔林口服剂量的患者进行了检查。血清哌克昔林浓度的测定表明,由于达到药物饱和的剂量不同,患者之间需要不同的剂量要求。如果要避免药物的副作用,血清哌克昔林浓度的测定至关重要。