Huang Yixuan, Shi Bing, Zheng Qian, Li Jingtao
State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Oral&Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, No.14 Ren Min Nan Road, Chengdu, Sichuan, 610041, China.
BMC Surg. 2025 Jul 30;25(1):326. doi: 10.1186/s12893-025-03038-w.
Flap dehiscence is a common complication observed after Furlow palatoplasty, but its impact on speech outcome is unclear. This study aimed to test the hypothesis that flap dehiscence following Furlow palatoplasty significantly increases the risk of adverse long-term speech outcomes.
This retrospective cohort study reviewed patients with soft cleft palate (SCP), submucous cleft palate (SMCP), or secondary velopharyngeal incompetence (VPI) who underwent Furlow palatoplasty from 2013 to 2023 at a tertiary hospital-based cleft center. The exposure variable was wound healing status, categorized as primary healing (without flap dehiscence), secondary healing (with flap dehiscence), or persistent fistulae formation. The location, size, and healing duration of flap dehiscence were also documented. The primary outcome was postoperative velopharyngeal function, assessed through standardized speech evaluations. Associations were analyzed using univariate and multivariate logistic regression models.
A total of 431 patients receiving Furlow palatoplasty were enrolled, with 12.5% reported flap dehiscence and 3.0% with persistent oronasal fistulae. For both primary cleft repair and secondary VPI correction, the occurrence of flap dehiscence and age at operation were identified as in significant correlation with postoperative velopharyngeal function. Patients with secondary healing demonstrated a higher rate of hypernasality and worse speech intelligibility. In addition, those with dehiscence size larger than 1cm demonstrated significantly higher rate of VPI than those less than 1cm.
Flap dehiscence is a significant prognostic factor in long-term speech outcomes following Furlow palatoplasty. Wound healing monitor is necessary for the comprehensive evaluation of cleft repair techniques.
皮瓣裂开是Furlow腭裂修复术后常见的并发症,但其对语音结果的影响尚不清楚。本研究旨在验证以下假设:Furlow腭裂修复术后皮瓣裂开显著增加长期不良语音结果的风险。
这项回顾性队列研究对2013年至2023年在一家三级医院腭裂中心接受Furlow腭裂修复术的软腭裂(SCP)、黏膜下腭裂(SMCP)或继发性腭咽闭合不全(VPI)患者进行了评估。暴露变量为伤口愈合状况,分为一期愈合(无皮瓣裂开)、二期愈合(有皮瓣裂开)或持续性瘘管形成。还记录了皮瓣裂开的位置、大小和愈合持续时间。主要结果是术后腭咽功能,通过标准化语音评估进行评估。使用单变量和多变量逻辑回归模型分析相关性。
共有431例接受Furlow腭裂修复术的患者入组,其中12.5%报告有皮瓣裂开,3.0%有持续性口鼻瘘。对于一期腭裂修复和二期VPI矫正,皮瓣裂开的发生和手术年龄均与术后腭咽功能显著相关。二期愈合的患者鼻音过重发生率较高,语音清晰度较差。此外,皮瓣裂开尺寸大于1cm的患者VPI发生率明显高于小于1cm的患者。
皮瓣裂开是Furlow腭裂修复术后长期语音结果的重要预后因素。伤口愈合监测对于腭裂修复技术的综合评估是必要的。