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超声引导下手术穿刺引流在化脓性肝脓肿早期治疗中的临床应用

Clinical application of ultrasound-guided surgical puncture and drainage in early treatment of pyogenic liver abscess.

作者信息

Qiu Feng, Yang Tian-Chi, Han Wei

机构信息

Department of General Surgery, Beijing Luhe Hospital, Capital Medical University, Beijing 101149, China.

出版信息

World J Gastrointest Surg. 2025 Jul 27;17(7):107544. doi: 10.4240/wjgs.v17.i7.107544.

Abstract

BACKGROUND

Pyogenic liver abscess (PLA) is a prevalent liver infection with gradual onset and severe symptoms, including fever, abdominal pain, jaundice, and vomiting. Complications like sepsis or toxic shock can also occur.

AIM

To investigate the clinical value of early ultrasound-guided percutaneous drainage (PCD) in PLA patients, specifically those with non-liquefied abscesses, and evaluate the feasibility of early intervention.

METHODS

This retrospective analysis included 143 patients with PLA who were admitted to the Department of General Surgery between January 2018 and March 2023. All patients underwent ultrasound-guided PCD. Based on the liquefaction status of the abscess, patients were divided into two groups: Liquefied group and non-liquefied group. Clinical outcomes, including puncture success rate, puncture duration, length of hospital stay, time to fever resolution, abscess shrinkage rate, and complication rates, were compared between the two groups.

RESULTS

The puncture success rate for all patients was 99.3%, with a postoperative complication rate of 5.59%, and no intraoperative deaths occurred. Compared to the liquefied group, the non-liquefied group had significantly shorter hospital stays (3.9 ± 1.8 days 5.1 ± 2.7 days), faster fever resolution (2.4 ± 1.1 days 4.9 ± 2.2 days), and quicker abscess shrinkage (> 50%) (4.7 ± 1.5 days 8.6 ± 3.3 days) ( < 0.05). There were no significant differences in puncture success rates or complication rates between the two groups.

CONCLUSION

Early ultrasound-guided PCD can be safely and effectively performed in PLA, even when the abscess is not fully liquefied or is non-liquefied, supporting the clinical feasibility of early intervention.

摘要

背景

化脓性肝脓肿(PLA)是一种常见的肝脏感染性疾病,起病隐匿,症状严重,包括发热、腹痛、黄疸和呕吐等。还可能发生败血症或中毒性休克等并发症。

目的

探讨早期超声引导下经皮穿刺引流(PCD)在PLA患者,特别是非液化性脓肿患者中的临床价值,并评估早期干预的可行性。

方法

本回顾性分析纳入了2018年1月至2023年3月期间在普通外科住院的143例PLA患者。所有患者均接受超声引导下PCD。根据脓肿的液化状态,将患者分为两组:液化组和非液化组。比较两组的临床结局,包括穿刺成功率、穿刺时间、住院时间、发热消退时间、脓肿缩小率和并发症发生率。

结果

所有患者的穿刺成功率为99.3%,术后并发症发生率为5.59%,无术中死亡病例。与液化组相比,非液化组的住院时间明显缩短(3.9±1.8天对5.1±2.7天),发热消退更快(2.4±1.1天对4.9±2.2天),脓肿缩小更快(>50%)(4.7±1.5天对8.6±3.3天)(<0.05)。两组的穿刺成功率和并发症发生率无显著差异。

结论

即使脓肿未完全液化或为非液化性,早期超声引导下PCD在PLA中也能安全有效地进行,支持早期干预的临床可行性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05de/12305221/dd40e5001551/wjgs-17-7-107544-g001.jpg

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