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美国医疗补助计划中抗肥胖药物的支出、使用情况及价格趋势:1999年至2023年的实证分析

Spending, utilization, and price trends for anti-obesity medications in U.S. Medicaid programs: an empirical analysis from 1999 to 2023.

作者信息

Alsuhibani Abdulrahman A, Alrasheed Marwan A, Alhomoud Ibrahim S, Alsahali Saud, Almalki Ziyad S, Guo Jeff Jianfei

机构信息

Department of Pharmacy Practice, College of Pharmacy, Qassim University, Buraydah, Saudi Arabia.

Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.

出版信息

Front Med (Lausanne). 2025 Jul 16;12:1537181. doi: 10.3389/fmed.2025.1537181. eCollection 2025.

Abstract

BACKGROUND

Obesity poses a significant public health and economic challenge in the United States (U.S.), with rising prevalence, particularly among individuals enrolled in Medicaid-the nation's public health insurance program for low-income populations. Anti-obesity medications (AOMs) have become integral to managing obesity, but trends in their utilization and spending within Medicaid remain underexplored.

OBJECTIVE

To examine Medicaid's utilization, reimbursement, and price trends for AOMs from 1999 to 2023.

METHODS

A retrospective analysis assessing the utilization, reimbursement, and pricing of older and newer AOMs. Yearly prescription numbers and reimbursement were calculated for seven AOMs billed through Medicaid between 1999 and 2023. The average expenditure per prescription was used as an indicator of drug pricing.

RESULTS

AOM prescriptions rose from 13,855 in 1999 to 938,663 in 2023, a 6,674% increase. Spending surged by over 77,805,466% due to the introduction of newer, more effective medications, including Wegovy and tirzepatide. The largest share of the market growth in 2023 was driven by these medications.

CONCLUSION

The significant increase in AOM utilization and spending highlights the growing burden of obesity on Medicaid, emphasizing the need for policy measures to manage rising costs and ensure equitable access to treatment.

摘要

背景

在美国,肥胖对公共卫生和经济构成了重大挑战,肥胖患病率不断上升,尤其是在参加医疗补助计划(Medicaid)的人群中,该计划是美国为低收入人群提供的公共医疗保险项目。抗肥胖药物(AOMs)已成为管理肥胖问题的重要组成部分,但医疗补助计划中其使用和支出的趋势仍未得到充分研究。

目的

研究1999年至2023年医疗补助计划中抗肥胖药物的使用、报销和价格趋势。

方法

进行一项回顾性分析,评估新旧抗肥胖药物的使用、报销和定价情况。计算了1999年至2023年期间通过医疗补助计划计费的七种抗肥胖药物的年度处方数量和报销情况。每张处方的平均支出用作药物定价指标。

结果

抗肥胖药物处方从1999年的13,855张增加到2023年的938,663张,增长了6,674%。由于引入了更新、更有效的药物,包括司美格鲁肽(Wegovy)和替尔泊肽(tirzepatide),支出激增超过77,805,466%。2023年市场增长的最大份额由这些药物推动。

结论

抗肥胖药物使用和支出的显著增加凸显了肥胖给医疗补助计划带来的日益沉重的负担,强调需要采取政策措施来控制成本上升,并确保公平获得治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2825/12307327/d28c79678d82/fmed-12-1537181-g001.jpg

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