Gourisaria Gourav, Sumanasan Navin, Ozen Goksu, Konduru Thejas Swaroop, Karunakaran Thozhuthumparambil Pradeep
Acute Internal Medicine, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, GBR.
Endocrinology and Diabetes, Royal Glamorgan Hospital, Cardiff, GBR.
Cureus. 2025 Jun 30;17(6):e87032. doi: 10.7759/cureus.87032. eCollection 2025 Jun.
Clozapine is an antipsychotic medication prescribed for patients who do not respond to or cannot tolerate standard antipsychotic treatments. It is also used to manage psychosis associated with Parkinson's disease. As a high-risk drug, clozapine requires strict monitoring. A rare but serious side effect is cardiomyopathy, which necessitates discontinuation of the medication. This report presents the case of a 42-year-old male patient admitted with recurrent falls and urinary sepsis while on clozapine. He exhibited persistent tachycardia and drowsiness and was diagnosed with cardiomyopathy, likely induced by clozapine.
氯氮平是一种抗精神病药物,用于治疗对标准抗精神病治疗无反应或无法耐受的患者。它也用于治疗与帕金森病相关的精神病。作为一种高风险药物,氯氮平需要严格监测。一种罕见但严重的副作用是心肌病,这需要停药。本报告介绍了一名42岁男性患者的病例,该患者在服用氯氮平期间因反复跌倒和尿脓毒症入院。他表现出持续性心动过速和嗜睡,被诊断为可能由氯氮平引起的心肌病。