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Selenium nanoparticles mitigate chlorpyrifos-induced nephrotoxicity by modulating oxidative stress, inflammation, and the SIRT1/Nrf2/HO-1 signaling pathway.

作者信息

Mahmoud Alaa A A, Mahmoud Ayman M, Abdel-Moneim Adel, Alnasser Sulaiman M, Alruhaimi Reem S, Hassanein Emad H M, El-Twab Sanaa M Abd

机构信息

Molecular Physiology Division, Zoology Department, Faculty of Science, Beni-Suef University, Beni-Suef, 62514, Egypt.

Department of Life Sciences, Faculty of Science and Engineering, Manchester Metropolitan University, Manchester, M1 5GD, UK.

出版信息

J Mol Histol. 2025 Jul 31;56(4):249. doi: 10.1007/s10735-025-10487-3.

DOI:10.1007/s10735-025-10487-3
PMID:40742471
Abstract
摘要

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本文引用的文献

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Antioxidant and renal protective effects of Nano-selenium on adenine-induced acute renal failure in canines.纳米硒对犬腺嘌呤诱导的急性肾衰竭的抗氧化及肾保护作用。
Ecotoxicol Environ Saf. 2024 Nov 15;287:117274. doi: 10.1016/j.ecoenv.2024.117274. Epub 2024 Nov 12.
2
Galangin attenuates chlorpyrifos-induced kidney injury by mitigating oxidative stress and inflammation and upregulating Nrf2 and farnesoid-X-receptor in rats.姜黄素通过减轻氧化应激和炎症以及上调 Nrf2 和法尼醇 X 受体来减轻氯吡磷诱导的大鼠肾脏损伤。
Environ Toxicol Pharmacol. 2024 Sep;110:104542. doi: 10.1016/j.etap.2024.104542. Epub 2024 Aug 22.
3
Selenium nanoparticles alleviate renal ischemia/reperfusion injury by inhibiting ferritinophagy via the XBP1/NCOA4 pathway.
硒纳米颗粒通过 XBP1/NCOA4 途径抑制铁蛋白自噬来减轻肾缺血/再灌注损伤。
Cell Commun Signal. 2024 Jul 25;22(1):376. doi: 10.1186/s12964-024-01751-2.
4
Farnesol prevents chlorpyrifos nephrotoxicity by modulating inflammatory mediators, Nrf2 and FXR and attenuating oxidative stress.法尼醇通过调节炎症介质、Nrf2 和 FXR 以及减轻氧化应激来预防毒死蜱的肾毒性。
Food Chem Toxicol. 2024 Aug;190:114788. doi: 10.1016/j.fct.2024.114788. Epub 2024 Jun 6.
5
Pesticides impacts on human health and the environment with their mechanisms of action and possible countermeasures.农药对人类健康和环境的影响及其作用机制与可能的应对措施。
Heliyon. 2024 Apr 4;10(7):e29128. doi: 10.1016/j.heliyon.2024.e29128. eCollection 2024 Apr 15.
6
Dihydroquercetin improves experimental acute liver failure by targeting ferroptosis and mitochondria-mediated apoptosis through the SIRT1/p53 axis.二氢槲皮素通过SIRT1/p53轴靶向铁死亡和线粒体介导的凋亡来改善实验性急性肝衰竭。
Phytomedicine. 2024 Jun;128:155533. doi: 10.1016/j.phymed.2024.155533. Epub 2024 Mar 16.
7
Exposure to the environmental pollutant chlorpyrifos induces hepatic toxicity through activation of the JAK/STAT and MAPK pathways.接触环境污染物毒死蜱会通过激活 JAK/STAT 和 MAPK 途径诱导肝毒性。
Sci Total Environ. 2024 Jun 10;928:171711. doi: 10.1016/j.scitotenv.2024.171711. Epub 2024 Mar 16.
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Life Sci. 2024 Mar 1;340:122445. doi: 10.1016/j.lfs.2024.122445. Epub 2024 Jan 24.
10
Biogenic Selenium Nanoparticles Synthesized with Alginate Oligosaccharides Alleviate Heat Stress-Induced Oxidative Damage to Organs in Broilers through Activating Nrf2-Mediated Anti-Oxidation and Anti-Ferroptosis Pathways.用海藻寡糖合成的生物源硒纳米颗粒通过激活Nrf2介导的抗氧化和抗铁死亡途径减轻热应激诱导的肉鸡器官氧化损伤。
Antioxidants (Basel). 2023 Nov 6;12(11):1973. doi: 10.3390/antiox12111973.