Bondarenko S V, Ushakova I P, Levit L F, Serebrennikova G A, Evstigneeva R P
Bioorg Khim. 1985 Oct;11(10):1385-90.
Incorporation of hemoglobin into vesicles and its oxidation were studied as a function of composition of the vesicular membrane containing erythrocyte membrane lipids as main components. The addition of negatively charged lipids such as phosphatidylserine and phosphatidic acid, was shown to considerably increase the extent of hemoglobin binding, while sphingomyelin did not produce such an effect. Cholesterol and dipalmitoylphosphatidylcholine stabilized oxyHb.
研究了血红蛋白掺入囊泡及其氧化过程，该过程是含有红细胞膜脂质作为主要成分的囊泡膜组成的函数。结果表明，添加带负电荷的脂质如磷脂酰丝氨酸和磷脂酸，可显著增加血红蛋白的结合程度，而鞘磷脂则没有这种作用。胆固醇和二棕榈酰磷脂酰胆碱可稳定氧合血红蛋白。
