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烧伤患儿发病率和死亡率中的中性粒细胞与淋巴细胞比值及血小板与淋巴细胞比值

Neutrophil-lymphocyte ratio and platelet-lymphocyte ratio in morbidity and mortality in children with burns.

作者信息

Bülbül Serap Samut, Akdeniz Sevda, Ceylan Alper, Saraç Ahmet, Güzel Murat, Ocak Metin, Görgün Selim

机构信息

Faculty of Medicine, Samsun University, Samsun, Turkey.

Samsun Training and Research Hospital, Samsun, Turkey.

出版信息

Pediatr Surg Int. 2025 Jul 31;41(1):239. doi: 10.1007/s00383-025-06145-0.

Abstract

OBJECTIVES

The aim of the present study was to investigate whether neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) rates have a role in morbidity and mortality in children who were hospitalized due to burns.

METHODS

A total of 282 patients between the ages of 0-18 who were hospitalized due to deep partial thickness and full thickness burns between 2018 and 2023 were included in the study.

RESULTS

The mean NLR value in deceased patients was found to be significantly higher than that in survivors (p < 0.036). The NLR value was found to be significantly positively associated with the duration of hospital stay (p < 0.001). The sensitivity and specificity of the 8.775 cutoff value for NLR in predicting mortality were determined to be 66.7% and 74.7%, respectively. There was no statistically significant difference between the PLR values of survivors and non-survivors (p = 0.926).

CONCLUSION

Despite PLR, the study indicates that the risk of morbidity and mortality is significantly higher in pediatric patients with high NLR values at the time of admission to the hospital, and that the NLR value provides important information about the clinical course and mortality in these patients.

摘要

目的

本研究旨在探讨中性粒细胞与淋巴细胞比值(NLR)和血小板与淋巴细胞比值(PLR)在因烧伤住院儿童的发病率和死亡率中是否起作用。

方法

本研究纳入了2018年至2023年间因深Ⅱ度和Ⅲ度烧伤住院的282例0至18岁患者。

结果

发现死亡患者的平均NLR值显著高于存活患者(p < 0.036)。发现NLR值与住院时间显著正相关(p < 0.001)。NLR预测死亡率的8.775临界值的敏感性和特异性分别确定为66.7%和74.7%。存活者和非存活者的PLR值之间无统计学显著差异(p = 0.926)。

结论

尽管有PLR,但该研究表明,入院时NLR值高的儿科患者发病和死亡风险显著更高,且NLR值为这些患者的临床病程和死亡率提供了重要信息。

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