Sarr Mbéré, Diop Malick, Bakhoum Abdoulaye Jacque, Doucoure Souleymane, Sow Doudou, Bâ Cheikh Tidiane, Sokhna Cheikh, Boissier Jérôme, Senghor Bruno
MINES, UCAD-IRD International Campus, Hann, 18524, Dakar, Senegal.
Department of Animal Biology, Cheikh Anta Diop University of Dakar, Dakar, Senegal.
Parasit Vectors. 2025 Jul 31;18(1):314. doi: 10.1186/s13071-025-06918-5.
Intestinal schistosomiasis, caused by Schistosoma mansoni, is endemic in both Africa and South America. In Senegal and Brazil, S. mansoni is transmitted by Biomphalaria pfeifferi and Biomphalaria glabrata, respectively. With increasing human migration from Senegal to the Americas, there is a potential risk of transferring parasite strains across continents. Understanding the compatibility between Schistosoma species and strains, and snail hosts is therefore essential. This study investigated the compatibility of two S. mansoni strains from Senegal (SmSEN) and Brazil (SmBRA) with both B. pfeifferi (BpSEN) and B. glabrata (BgBRA) originating from Senegal and Brazil, respectively.
Four infection combinations were performed: (1) SmSEN + BpSEN (2) SmSEN + BgBRA (3) SmBRA + BgBRA, and (4) SmBRA + BpSEN. A minimum of 72 snails were individually exposed to five miracidia per combination.
The data show high compatibility between Brazilian and Senegalese S. mansoni with B. pfeifferi (92.4% and 77.3%, respectively). In contrast, both strains showed a low compatibility with B. glabrata, with rates of 67.3 and 48% for the Brazilian and Senegalese S. mansoni, respectively.
The high compatibility between S. mansoni and Biomphalaria species from Senegal and Brazil highlights the adaptability of S. mansoni to infect different Biomphalaria species across geographically distinct regions. These findings emphasize the importance of monitoring areas at risk of schistosomiasis emergence, particularly in the context of human migration and the invasive spread of Biomphalaria species into novel environments.
由曼氏血吸虫引起的肠道血吸虫病在非洲和南美洲均为地方病。在塞内加尔和巴西，曼氏血吸虫分别由费氏拟钉螺和光滑双脐螺传播。随着人类从塞内加尔向美洲的迁移增加，存在跨大陆传播寄生虫菌株的潜在风险。因此，了解血吸虫种类和菌株与蜗牛宿主之间的兼容性至关重要。本研究调查了来自塞内加尔（SmSEN）和巴西（SmBRA）的两种曼氏血吸虫菌株分别与源自塞内加尔和巴西的费氏拟钉螺（BpSEN）和光滑双脐螺（BgBRA）的兼容性。
进行了四种感染组合：（1）SmSEN + BpSEN（2）SmSEN + BgBRA（3）SmBRA + BgBRA，以及（4）SmBRA + BpSEN。每个组合至少72只蜗牛分别暴露于五只毛蚴。
数据显示巴西和塞内加尔的曼氏血吸虫与费氏拟钉螺的兼容性很高（分别为92.4%和77.3%）。相比之下，两种菌株与光滑双脐螺的兼容性都很低，巴西和塞内加尔的曼氏血吸虫的感染率分别为67.3%和48%。
塞内加尔和巴西的曼氏血吸虫与拟钉螺属物种之间的高兼容性突出了曼氏血吸虫感染地理上不同地区的不同拟钉螺属物种的适应性。这些发现强调了监测有血吸虫病出现风险地区的重要性，特别是在人类迁移以及拟钉螺属物种侵入新环境的背景下。
