iPSC-based merlin-deficient Schwann cell-like spheroids as an system for studying pathogenesis.
作者信息
Catasús Núria, Casals-Sendra Gemma, Torres-Martin Miguel, Rosas Inma, Kuebler Bernd, Mazuelas Helena, Amilibia Emilio, Aran Begoña, Veiga Anna, Raya Ángel, Gel Bernat, Blanco Ignacio, Serra Eduard, Carrió Meritxell, Castellanos Elisabeth
机构信息
Clinical Genomics Research Group, Germans Trias i Pujol Research Institute (IGTP), Can Ruti Campus, Badalona, Barcelona 08916, Spain.
PhD Program in Genetics, University of Barcelona, Barcelona 08007, Spain.
出版信息
Genes Dis. 2025 Mar 27;12(6):101615. doi: 10.1016/j.gendis.2025.101615. eCollection 2025 Nov.
Abstract
摘要
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本文引用的文献
1
Cellular mechanisms of heterogeneity in NF2-mutant schwannoma.NF2 突变型神经鞘瘤异质性的细胞机制。
Nat Commun. 2023 Mar 21;14(1):1559. doi: 10.1038/s41467-023-37226-0.
2
Updated diagnostic criteria and nomenclature for neurofibromatosis type 2 and schwannomatosis: An international consensus recommendation.神经纤维瘤病 2 型和雪旺细胞瘤病的更新诊断标准和命名：国际共识建议。
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Modeling iPSC-derived human neurofibroma-like tumors in mice uncovers the heterogeneity of Schwann cells within plexiform neurofibromas.在小鼠中建立 iPSC 来源的人类神经纤维瘤样肿瘤模型揭示了神经丛状神经纤维瘤中雪旺细胞的异质性。
Cell Rep. 2022 Feb 15;38(7):110385. doi: 10.1016/j.celrep.2022.110385.
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New developments in neurofibromatosis type 2 and vestibular schwannoma.2型神经纤维瘤病和前庭神经鞘瘤的新进展。
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Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2.小鼠中的条件性双等位基因Nf2突变促进了人类2型神经纤维瘤病的表现。
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