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面部瘢痕早期治疗的多模式方法：病例报告

A Multimodal Approach to the Early Treatment of a Facial Scar: A Case Report.

作者信息

Akl Jennifer, El Hajj Hamad, Jeha Dima, Habre Maya

机构信息

Department of Dermatology Faculty of Medicine, University of Balamand Koura Lebanon.

Department of Dermatology Faculty of Medicine, Saint Georges Hospital University Medical Center, Saint George University of Beirut Beirut Lebanon.

出版信息

Clin Case Rep. 2025 Jul 30;13(8):e70719. doi: 10.1002/ccr3.70719. eCollection 2025 Aug.

DOI:10.1002/ccr3.70719
PMID:40746774
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12311219/
Abstract

Facial scarring is associated with considerable psychosocial distress and can adversely affect overall quality of life. The combination of intralesional botulinum toxin injection and laser treatments in the early stage of wound healing markedly enhances scar appearance and improves cosmetic and psychological outcomes.

摘要

面部瘢痕与相当大的心理社会困扰相关，并且会对整体生活质量产生不利影响。在伤口愈合早期联合病灶内注射肉毒杆菌毒素和激光治疗可显著改善瘢痕外观，提高美容和心理效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/12311219/b5ce5b8e146d/CCR3-13-e70719-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/12311219/6da99f97b791/CCR3-13-e70719-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/12311219/b5ce5b8e146d/CCR3-13-e70719-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/12311219/6da99f97b791/CCR3-13-e70719-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/12311219/b5ce5b8e146d/CCR3-13-e70719-g001.jpg

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本文引用的文献

1
Efficacy and safety of sequential treatment with botulinum toxin type A, fractional CO2 laser, and topical growth factor for hypertrophic scar management: a retrospective analysis.A型肉毒毒素序贯治疗、分束二氧化碳激光和局部生长因子治疗增生性瘢痕的疗效和安全性：回顾性分析。
Sci Rep. 2024 Nov 8;14(1):27233. doi: 10.1038/s41598-024-78094-y.
2
Timing of Laser Intervention on Facial Scars: A 3D Imaging and Scar Scale Analysis in a Retrospective Study.激光干预面部瘢痕的时机：回顾性研究中的三维成像和瘢痕量表分析。
Lasers Surg Med. 2024 Nov;56(9):770-775. doi: 10.1002/lsm.23846. Epub 2024 Sep 22.
3
Early postoperative interventions in the prevention and management of thyroidectomy scars.
甲状腺切除术后瘢痕预防与处理的早期干预措施
Front Physiol. 2024 Mar 6;15:1341287. doi: 10.3389/fphys.2024.1341287. eCollection 2024.
4
Fractional Er:YAG laser versus fractional CO2 laser in the treatment of immature and mature scars: a comparative randomized study.铒钇铝石榴石分次激光与二氧化碳分次激光治疗未成熟和成熟瘢痕的比较随机研究
Arch Dermatol Res. 2024 Jan 18;316(2):75. doi: 10.1007/s00403-023-02764-6.
5
Efficacy of Botulinum Toxin Type A for Prevention of Post-Mastectomy Scar in Transmen: A Prospective, Randomized Study.A型肉毒毒素预防跨性别男性乳房切除术后瘢痕的疗效：一项前瞻性、随机研究。
Toxins (Basel). 2023 Oct 31;15(11):636. doi: 10.3390/toxins15110636.
6
Clinical trial to evaluate the efficacy of botulinum toxin type A injection for reducing scars in patients with forehead laceration: A double-blinded, randomized controlled study.评估A型肉毒杆菌毒素注射对减轻前额裂伤患者瘢痕疗效的临床试验：一项双盲、随机对照研究。
Medicine (Baltimore). 2019 Aug;98(34):e16952. doi: 10.1097/MD.0000000000016952.
7
Laser treatments in early wound healing improve scar appearance: a randomized split-wound trial with nonablative fractional laser exposures vs. untreated controls.早期伤口愈合中的激光治疗可改善疤痕外观：非剥脱性点阵激光与未治疗对照的随机分割伤口试验。
Br J Dermatol. 2018 Dec;179(6):1307-1314. doi: 10.1111/bjd.17076. Epub 2018 Sep 30.