Huynh Tran Ngoc An, Trinh Darren, Chandrananth Janan, Sewell James
Department of Urology, Monash Health, Melbourne, Victoria 3806, Australia.
Department of Orthopedics, Peninsula Health, Melbourne, Victoria 3199, Australia.
Bladder (San Franc). 2025 Mar 21;12(1):e21200041. doi: 10.14440/bladder.2024.0077. eCollection 2025.
Bladder cancer (BCa) frequently metastasizes to bones, typically affecting the spine and pelvis.
Presented here is a case of rare extensive distal tibia metastasis in an 84-year-old female with invasive high-grade urothelial carcinoma, who suffered from rapidly progressive ankle pain and reduced mobility. Imaging and biopsy confirmed metastatic urothelial carcinoma in the tibia, which was managed with surgical fixation and palliative radiotherapy. Although bone metastases in BCa commonly affect other sites, clinicians should consider atypical locations like the tibia in patients with unexplained bone pain.
Early diagnosis and intervention are essential for improving patient outcomes and quality of life.
膀胱癌（BCa）常转移至骨骼，通常累及脊柱和骨盆。
本文呈现了一例84岁患有浸润性高级别尿路上皮癌的女性发生罕见的胫骨远端广泛转移的病例，该患者出现快速进展的踝关节疼痛和活动能力下降。影像学检查和活检证实胫骨存在转移性尿路上皮癌，通过手术固定和姑息性放疗进行治疗。尽管膀胱癌的骨转移通常累及其他部位，但对于有不明原因骨痛的患者，临床医生应考虑像胫骨这样的非典型部位。
早期诊断和干预对于改善患者预后和生活质量至关重要。
