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使用海藻酸钠和奇亚籽胶对源自藻类的生物活性肽进行包封。

Encapsulation of bioactive peptides derived from algae using calcium alginate and chia gum.

作者信息

Jafarirad Sara, Nateghi Leila, Moslemi Masoumeh, Afshari Kian Pahlevan, Khosravi-Darani Kianoush

机构信息

Department of Food Science and Technology, VaP.C., Islamic Azad University, Varamin, Iran.

Halal Research Center of IRI., Iran Food and Drug Administration, Ministry of Health and Medical Education, Tehran, Iran.

出版信息

Food Chem X. 2025 Jul 13;29:102787. doi: 10.1016/j.fochx.2025.102787. eCollection 2025 Jul.

Abstract

This study aimed to encapsulate bioactive peptides derived from Sargassum angustifolium protein isolate within calcium alginate and chia seed gum matrices using freeze-drying. The encapsulated microbeads and microcapsules were evaluated based on encapsulation efficiency (EE), surface charge (zeta potential), microstructure, chemical composition, and thermal properties. Results indicated that Alg-SAPH exhibited a higher EE compared to CSG-SAPH. Alg-SAPH microbeads displayed a more negative zeta potential than CSG-SAPH microcapsules, suggesting enhanced electrostatic stability. Structural analysis revealed that Alg-SAPH formed interconnected microbead chains, whereas CSG-SAPH demonstrated a shell-like morphology. Differential scanning calorimetry (DSC) analysis showed that Alg-SAPH had a lower melting point compared to CSG-SAPH, whereas its transition enthalpy was significantly higher. The findings suggest that encapsulating SAPH within biopolymeric carriers enhances its stability and bioavailability, offering a promising approach for incorporating bioactive peptides into functional foods and therapeutic applications while masking their undesirable taste.

摘要

本研究旨在通过冷冻干燥将源自狭叶马尾藻蛋白分离物的生物活性肽包封在海藻酸钙和奇亚籽胶基质中。基于包封效率(EE)、表面电荷(zeta电位)、微观结构、化学成分和热性能对包封的微珠和微胶囊进行了评估。结果表明,与CSG-SAPH相比,Alg-SAPH表现出更高的包封效率。Alg-SAPH微珠的zeta电位比CSG-SAPH微胶囊更负,表明其静电稳定性增强。结构分析表明,Alg-SAPH形成了相互连接的微珠链,而CSG-SAPH呈现出壳状形态。差示扫描量热法(DSC)分析表明,与CSG-SAPH相比,Alg-SAPH的熔点较低,而其转变焓显著更高。研究结果表明,将SAPH包封在生物聚合物载体中可提高其稳定性和生物利用度,为将生物活性肽纳入功能性食品和治疗应用同时掩盖其不良味道提供了一种有前景的方法。

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