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[情绪应激下大鼠的红细胞功能]

[Erythrocyte function of rats under emotional stress].

作者信息

Vitrichenko E E

出版信息

Biull Eksp Biol Med. 1985 Dec;100(12):675-7.

PMID:4074867
Abstract

The effect of neurogenic stress of the conflict-of-afferent-excitations-type on the oxidizing erythrocyte properties and qualitative and quantitative red blood changes has been studied. Neurogenic stress was demonstrated to significantly affect the erythrocyte functional state in rats. Activation of free-radical oxidation of erythrocyte membrane lipids took place, provoking changes in their permiability and disorders of oxygen fixation and release. It is suggested that these changes may be the underlying mechanism of the developing tissue hypoxia and play a leading role in the pathogenesis of cardiovascular diseases.

摘要

研究了传入兴奋冲突型神经源性应激对氧化红细胞特性以及红细胞质和量变化的影响。结果表明,神经源性应激对大鼠红细胞功能状态有显著影响。红细胞膜脂质的自由基氧化被激活,引发其通透性改变以及氧固定和释放紊乱。这些变化可能是组织缺氧发展的潜在机制,并在心血管疾病的发病机制中起主导作用。

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