Kang Mengyang, Zhao Yang, Meng Yan, Ma Qiang, Zhang Junbo, Qin Hao, Tian Hongyan
Department of Peripheral Vascular Diseases, The First Affiliated Hospital of Xi'an Jiaotong University, Shaanxi, China.
PLoS One. 2025 Aug 1;20(8):e0328817. doi: 10.1371/journal.pone.0328817. eCollection 2025.
The mid-term outcomes of using the Castor single branched stent graft to treat patients with type B acute aortic syndromes (AASs) involving the left subclavian artery (LSA) were unclear. This study aims to evaluate the mid-term efficacy of the Castor single branched stent graft in the treatment of type B AASs involving the LSA.
The retrospective study enrolled patients with type B AASs involving the LSA who were consecutively admitted to our hospital between January 1, 2019 and October 30, 2023. Patients underwent thoracic endovascular aortic repair (TEVAR) using the Castor device. The clinical data of these patients were collected, and their outcomes were followed.
This study included 106 patients, comprising those presenting with aortic dissection (AD) (n = 93), penetrating aortic ulcer (PAU) (n = 9), and intramural haematoma (IMH) (n = 4). All patients achieved the technical success. After a median follow-up period of 454 days (range: 359-771 days), all patients demonstrated survival, with 14 (14.4%) patients experiencing complications, including acute myocardial infarction (AMI, n = 1), endoleaks (n = 7), stenosis of the branched section(n = 3), stent graft-induced new entry tear (SINE, n = 2), and progressive aortic dilation (n = 1). Among the endoleaks, there were 1 Type Ib, 2 Type II, and 4 Type IV cases. Among the enrolled patients, two required re-intervention. No retrograde type A aortic dissection (RTAD), paraplegia or stroke were observed during the follow-up period.
The Castor device provided an easily manipulated, safe, and effective treatment option for patients with type B AASs involving the LSA.
使用Castor单分支覆膜支架治疗累及左锁骨下动脉(LSA)的B型急性主动脉综合征(AAS)患者的中期疗效尚不清楚。本研究旨在评估Castor单分支覆膜支架治疗累及LSA的B型AAS的中期疗效。
本回顾性研究纳入了2019年1月1日至2023年10月30日期间连续入住我院的累及LSA的B型AAS患者。患者使用Castor装置进行胸主动脉腔内修复术(TEVAR)。收集这些患者的临床资料,并对其预后进行随访。
本研究纳入106例患者,包括主动脉夹层(AD)患者93例、穿透性主动脉溃疡(PAU)患者9例、壁内血肿(IMH)患者4例。所有患者均获得技术成功。中位随访期为454天(范围:359 - 771天),所有患者均存活,14例(14.4%)患者出现并发症,包括急性心肌梗死(AMI,1例)、内漏(7例)、分支段狭窄(3例)、覆膜支架引起的新破口撕裂(SINE,2例)和主动脉进行性扩张(1例)。在内漏中,有1例Ib型、2例II型和4例IV型病例。在纳入的患者中两位患者需要再次干预。随访期间未观察到逆行性A型主动脉夹层(RTAD)、截瘫或中风。
Castor装置为累及LSA的B型AAS患者提供了一种易于操作、安全有效的治疗选择。