Physick-Sheard P W, Maxie M G, Palmer N C, Gaul C
Can J Comp Med. 1985 Oct;49(4):429-33.
Valvular competency of the foramen ovale (patent foramen ovale) is regarded as a common finding in the neonatal foal and usually occurs in isolation. True atrial septal defects appear to be uncommon and are usually associated with other congenital cardiac lesions. The present report describes a case of atrial septal defect type 1 (persistent ostium primum) complicated by hypoplastic right ventricle, and tricuspid dysplasia, in a Welsh Mountain pony foal, and discusses the embryogenesis of the abnormality. A critical review of the literature suggests that atrial septal defects may occur more frequently than they are reported, and that on occasion they may be described erroneously as patent foramen ovale. The clinical significance of uncomplicated discontinuity of the atrial septum is slight, depending upon the size and location of the defect. Complicated atrial septal defects vary in clinical significance according to the nature of the associated defects.
卵圆孔（卵圆孔未闭）的瓣膜功能不全在新生马驹中被视为常见表现，且通常单独出现。真正的房间隔缺损似乎并不常见，通常与其他先天性心脏病变相关。本报告描述了一匹威尔士山地小马驹发生的1型房间隔缺损（原发孔持续存在），并伴有右心室发育不全和三尖瓣发育异常的病例，并讨论了该异常的胚胎发生过程。对文献的严格审查表明，房间隔缺损的发生率可能比报道的更高，而且有时可能会被错误地描述为卵圆孔未闭。单纯性房间隔连续性中断的临床意义较小，这取决于缺损的大小和位置。复杂的房间隔缺损根据相关缺损的性质，其临床意义各不相同。
