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非洲区域人口与流行病学转变的比较分析:对公共卫生的政策影响

A comparative analysis of Africa's regional demographic and epidemiological transitions: Policy implications for public health.

作者信息

Ciccacci Fausto, Doro Annamaria, Basile Francesca, Iazzolino Chiara, Cicala Mariagrazia, Carestia Mariachiara, Mosconi Claudia, De Santo Carolina, Germano Paola, Liotta Giuseppe, Orlando Stefano

机构信息

Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.

DREAM Program, Community of Sant'Egidio, Rome, Italy.

出版信息

Public Health. 2025 Oct;247:105836. doi: 10.1016/j.puhe.2025.105836. Epub 2025 Aug 1.

Abstract

OBJECTIVES

Demographic and epidemiological changes have redefined public health priorities globally. Africa is undergoing an unprecedented demographic and epidemiological transformation with implications for public health. This study aims to provide a comparative analysis of these transitions across different African regions.

STUDY DESIGN

This is an observational descriptive study based on study utilizes secondary data from the World Bank and the Global Burden of Disease database to analyze demographic and epidemiological trends in Africa from 2000 to 2019.

METHODS

This study utilizes secondary data from the World Bank and the Global Burden of Disease database to analyze demographic and epidemiological trends in Africa from 2000 to 2019. The analysis is conducted on a regional basis, categorizing Africa into Northern, Western, Central, Eastern, and Southern regions. Birth rates, death rates, and life expectancy were extracted from the World Bank's open database for the years 1960-2020, and disease burden, categorized as communicable diseases (CDs), non-communicable diseases (NCDs) and injuries, were extracted from the Global Burden of Disease (GBD) study for the years 1990-2019 using both mortality data and disability adjusted life years (DALY).

RESULTS

Demographic and epidemiological transitions varied significantly. Northern Africa saw birth rates decline (50 per 1000 in 1960 to 20 in 2020), while population growth was most pronounced in Eastern Africa (70-330 million). The epidemiological transition showed a shift from CDs to NCDs across all regions. In Northern Africa, there was a decline in CDs, while NCDs increased (CD deaths: 279,529 in 1990 to 95,491 in 2019; CD DALYs: 25.9 million to 7.5 million; NCD deaths: 513,284 to 923,619; NCD DALYs: 25.2 million to 39.6 million). In contrast, the rest of Africa experienced slower progress in reducing CDs. In Southern Africa, after the peak of CD-related deaths in 2000, the burden of CDs declined, and today the disease burden is almost evenly split between CDs and NCDs (CD deaths: 754,169; NCD deaths: 543,419 in 2019).

CONCLUSION

These findings suggest the need for region-specific public health strategies across Africa. Northern and Southern Africa should prioritize NCD prevention and management, with early detection, care, and lifestyle interventions. Western and Central Africa require sustained infectious disease control, reinforcing vaccination, treatment access, and surveillance, while also addressing the rising burden of NCDs.

摘要

目标

人口结构和流行病学变化重新定义了全球公共卫生重点。非洲正在经历前所未有的人口结构和流行病学转变,对公共卫生产生影响。本研究旨在对非洲不同地区的这些转变进行比较分析。

研究设计

这是一项观察性描述性研究,该研究利用世界银行和全球疾病负担数据库的二手数据,分析2000年至2019年非洲的人口结构和流行病学趋势。

方法

本研究利用世界银行和全球疾病负担数据库的二手数据,分析2000年至2019年非洲的人口结构和流行病学趋势。分析按区域进行,将非洲分为北部、西部、中部、东部和南部地区。从世界银行开放数据库中提取1960 - 2020年的出生率、死亡率和预期寿命,并使用死亡率数据和伤残调整生命年(DALY),从全球疾病负担(GBD)研究中提取1990 - 2019年归类为传染病(CD)、非传染病(NCD)和伤害的疾病负担。

结果

人口结构和流行病学转变差异显著。北非的出生率下降(从1960年的每1000人50例降至2020年的20例),而东非的人口增长最为显著(从7000万增至3.3亿)。流行病学转变显示所有地区都从传染病转向了非传染病。在北非,传染病减少,而非传染病增加(传染病死亡人数:1990年为279,529例,2019年为95,491例;传染病DALY:从2590万降至750万;非传染病死亡人数:从513,284例增至923,619例;非传染病DALY:从2520万增至3960万)。相比之下,非洲其他地区在减少传染病方面进展较慢。在南非,2000年与传染病相关的死亡人数达到峰值后,传染病负担下降,如今疾病负担在传染病和非传染病之间几乎平分(传染病死亡人数:754,169例;2019年非传染病死亡人数:543,419例)。

结论

这些发现表明非洲需要针对各地区的公共卫生策略。北非和南非应将非传染病的预防和管理作为重点,进行早期检测、护理和生活方式干预。西非和中非需要持续控制传染病,加强疫苗接种、治疗可及性和监测,同时应对不断上升的非传染病负担。

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