皮质醇在体外抑制辐射转化。
Cortisol suppresses radiation transformation in vitro.
作者信息
Kennedy A R
出版信息
Cancer Lett. 1985 Dec;29(3):289-92. doi: 10.1016/0304-3835(85)90139-9.
PMID:4075298
Abstract
It is reported that 10(-7) M cortisol has a significant suppressive effect on radiation-induced transformation in vitro in C3H10T1/2 cells. Previously reported data showed a significant enhancing effect for similar experiments performed with cortisone. Thus, these two structurally similar glucocorticoid hormones have opposite effects on transformation induced by ionizing radiation.
摘要
据报道，10⁻⁷M的皮质醇对C3H10T1/2细胞的体外辐射诱导转化具有显著的抑制作用。先前报道的数据表明，在使用可的松进行的类似实验中存在显著的增强作用。因此，这两种结构相似的糖皮质激素对电离辐射诱导的转化具有相反的作用。
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