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软性输尿管镜检查术后的尿路感染:巴勒斯坦西岸的一项前瞻性队列研究

Postoperative urinary tract infections following flexible ureteroscopy: a prospective cohort study in the West bank of Palestine.

作者信息

Mhamid Aaisha, Taha Rand, Ibrahem Rasheed, Hijaz Hatim, Bustame Samer, Shawahna Ramzi

机构信息

Department of Medicine, Faculty of Medicine and Allied Health Sciences, An-Najah National University, Nablus, Palestine.

An-Najah National University Hospital, Nablus, Palestine.

出版信息

BMC Urol. 2025 Aug 2;25(1):187. doi: 10.1186/s12894-025-01888-3.

DOI:10.1186/s12894-025-01888-3
PMID:40753392
Abstract

BACKGROUND

Reports on the incidence of urinary tract infections following flexible ureteroscopy in Palestine are scarce. This study aimed to assess the incidence of urinary tract infections after flexible ureteroscopy and to identify the risk factors that predict their occurrence among patients treated with this procedure in Palestinian clinical practice.

METHODS

This was a prospective cohort study that aimed to assess the incidence rate of postoperative urinary tract infections among patients who underwent flexible ureteroscopy in Palestinian clinical practice. The study was conducted between October 2023 and January 2025 in four different hospitals in the West Bank of Palestine.

RESULTS

A total of 253 patients were included in this study. Of the patients, 31 (12.3%) had urinary tract infections. Enterococcus faecalis was the most common causative agent. Multiple linear regression showed that the occurrence of post-flexible ureteroscopy urinary tract infections was significantly predicted by the postoperative red blood cell count (p-value = 0.033). Multivariate logistic regression demonstrated that patients with a documented urinary tract infection within the preceding 90 days had significantly greater odds of developing a post-flexible ureteroscopy urinary tract infection (OR = 3.34; 95% CI: 1.35-19.82). Furthermore, the absence of preoperative prophylactic antibiotic administration was independently associated with increased risk (OR = 4.66; 95% CI: 1.29-16.81) for a post-flexible ureteroscopy urinary tract infection.

CONCLUSION

The incidence rate of post-flexible ureteroscopy urinary tract infections in Palestinian clinical practice was within the range reported globally. The findings of this study emphasize the need for tailored, preventive measures, including enhanced preoperative risk assessment, optimized antibiotic management, and rigorous postoperative surveillance.

摘要

背景

关于巴勒斯坦地区软性输尿管镜检查后尿路感染发生率的报告很少。本研究旨在评估软性输尿管镜检查后尿路感染的发生率,并确定在巴勒斯坦临床实践中接受该手术的患者中预测其发生的危险因素。

方法

这是一项前瞻性队列研究,旨在评估巴勒斯坦临床实践中接受软性输尿管镜检查的患者术后尿路感染的发生率。该研究于2023年10月至2025年1月在巴勒斯坦西岸的四家不同医院进行。

结果

本研究共纳入253例患者。其中,31例(12.3%)发生尿路感染。粪肠球菌是最常见的病原体。多元线性回归显示,术后红细胞计数显著预测了软性输尿管镜检查后尿路感染的发生(p值 = 0.033)。多因素logistic回归表明,在过去90天内有尿路感染记录的患者发生软性输尿管镜检查后尿路感染的几率显著更高(OR = 3.34;95% CI:1.35 - 19.82)。此外,术前未给予预防性抗生素独立增加了软性输尿管镜检查后尿路感染的风险(OR = 4.66;95% CI:1.29 - 16.81)。

结论

巴勒斯坦临床实践中软性输尿管镜检查后尿路感染的发生率在全球报告的范围内。本研究结果强调了采取针对性预防措施的必要性,包括加强术前风险评估、优化抗生素管理和严格的术后监测。

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Randomized comparison of effect of standard antibiotic prophylaxis versus enhanced prophylactic measures on rate of urinary tract infection after flexible ureteroscopy.
标准抗生素预防措施与强化预防措施对输尿管软镜检查术后尿路感染发生率影响的随机对照比较
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Global and Regional Burden of Bacterial Antimicrobial Resistance in Urinary Tract Infections in 2019.2019年全球及地区尿路感染中细菌抗菌药物耐药负担
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Endoscopic management of upper tract urothelial carcinoma-tips and tricks.上尿路尿路上皮癌的内镜治疗——技巧与窍门
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A middle east systematic review and meta-analysis of bacterial urinary tract infection among renal transplant recipients; Causative microorganisms.中东地区肾移植受者细菌性尿路感染的系统评价和荟萃分析;致病微生物。
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