Kang Tao, Chen Weiyou, Huang Longao, Xu Hongyuan, Jiang Hua
Department of Spine Surgery, The First Affiliated Hospital of Guangxi Medical University, 6 Shuangyong Road, Nanning, Guangxi Zhuang Autonomous Region, 530021, China.
BMC Musculoskelet Disord. 2025 Aug 2;26(1):743. doi: 10.1186/s12891-025-08966-5.
This study aimed to explore radiographic differences in odontoid parameters between subjects with and without degenerative cervical spondylosis (DCS).
Lateral cervical X-rays and magnetic resonance imaging (MRI) from 51 healthy subjects (control group) and 107 DCS patients (case group) were retrospectively reviewed. The odontoid parameters including odontoid incidence (OI), odontoid tilt (OT), and related cervical sagittal parameters were measured: C2 slope (C2S), C0-2 angle (C0-2), C2-7 angle (cervical lordosis [CL]), T1 slope (T1S), and T1S minus cervical lordosis (T1S - CL). An independent-samples t test and the Wilcoxon rank-sum test were used to compare these parameters between the two groups. Spearman's correlation analysis assessed the correlations among these parameters. The formula CL = 0.36 × OI - 0.67 × OT - 0.69 × T1S was used to predict CL and confirm its efficacy.
The OI and OT were 15.67° ± 4.41° and 9.42° ± 4.66° in healthy subjects and 18.84° ± 3.41° and 4.47° ± 5.93° in DCS patients, with significant differences observed between the two groups (p < 0.001). In healthy subjects and DCS patients, OI and OT were correlated with C2S, C0-2, C2-7, and T1S - CL. The formula for predicting CL had predictive efficacy in healthy subjects (R = 0.88) and patients with DCS (R = 0.64).
OI and OT serve as valuable supplements to the established parameters for evaluating and predicting normal cervical lordosis, aiding in assessing cervical spine balance and guiding therapeutic strategies to restore it.
本研究旨在探讨有无退行性颈椎病（DCS）的受试者之间齿突参数的影像学差异。
回顾性分析51名健康受试者（对照组）和107名DCS患者（病例组）的颈椎侧位X线片和磁共振成像（MRI）。测量齿突参数，包括齿突发生率（OI）、齿突倾斜度（OT）以及相关的颈椎矢状面参数：C2斜率（C2S）、C0-2角（C0-2）、C2-7角（颈椎前凸[CL]）、T1斜率（T1S）以及T1S减去颈椎前凸（T1S - CL）。采用独立样本t检验和Wilcoxon秩和检验比较两组间这些参数。Spearman相关分析评估这些参数之间的相关性。使用公式CL = 0.36×OI - 0.67×OT - 0.69×T1S预测CL并确认其有效性。
健康受试者的OI和OT分别为15.67°±4.41°和9.42°±4.66°，DCS患者的分别为18.84°±3.41°和4.47°±5.93°，两组间差异有统计学意义（p < 0.001）。在健康受试者和DCS患者中，OI和OT与C2S、C0-2、C2-7以及T1S - CL相关。预测CL的公式在健康受试者（R = 0.88）和DCS患者（R = 0.64）中具有预测效力。
OI和OT是评估和预测正常颈椎前凸的既定参数的有价值补充，有助于评估颈椎平衡并指导恢复颈椎平衡的治疗策略。
