Holikulov Utkirjon, Trabelsi Sonia, Marouani Houda, Roisnel Thierry, Al-Dossary Omar M, Jumabaev Abduvakhid, Issaoui Noureddine
Department of Optics and Spectroscopy, Samarkand State University, 15, University Boulevard, 140104 Samarkand, Uzbekistan.
University of Carthage, Faculty of Sciences of Bizerte, LR13ES08, Laboratory of Material Chemistry, 7021 Bizerte, Tunisia.
Ann Pharm Fr. 2025 Aug 5. doi: 10.1016/j.pharma.2025.07.010.
This work presents a comprehensive study of the crystal structure, spectral properties (IR and UV-Vis), thermal behavior, and antimicrobial activity of homopiperazinium dichromate (CH1N)CrO(VI). X-ray diffraction reveals that the compound crystallizes in the monoclinic space group P2/c, with unit cell dimensions a=8.7275(8)Å, b=10.5769(11)Å, and c=14.7467(10)Å and β=122.941(4)°. The crystal packing is stabilized by intermolecular N-H…O and C-H…O hydrogen bonds, with Hirshfeld surface analysis revealing dominant O…H/H…O interactions contributing 80.5% to the overall crystal cohesion. UV-Vis absorption bands are observed at 279, 354, and 446nm, with an estimated band gap energy of 3.019eV, indicating high stability and moderate optical activity. Thermal analysis shows an intense endothermic fusion peak followed by continuous decomposition, leading to chromium oxide formation. Antimicrobial tests demonstrate significant inhibition activity against tested pathogens, including notable antifungal effects against Candida albicans. These results highlight the potential of this hybrid material in antimicrobial development and photochemical applications.
这项工作对重铬酸高哌嗪鎓（CH₁N）₂CrO(VI)的晶体结构、光谱性质（红外和紫外可见）、热行为及抗菌活性进行了全面研究。X射线衍射表明，该化合物结晶于单斜空间群P2/c中，晶胞参数为a = 8.7275(8)Å，b = 10.5769(11)Å，c = 14.7467(10)Å，β = 122.941(4)°。晶体堆积通过分子间N-H…O和C-H…O氢键得以稳定，Hirshfeld表面分析显示，占主导的O…H/H…O相互作用对整体晶体凝聚的贡献为80.5%。在279、354和446nm处观察到紫外可见吸收带，估计带隙能量为3.019eV，表明其具有高稳定性和适度的光学活性。热分析显示有一个强烈的吸热熔融峰，随后是连续分解，生成氧化铬。抗菌测试表明，该化合物对受试病原体具有显著的抑制活性，包括对白色念珠菌有明显的抗真菌作用。这些结果凸显了这种杂化材料在抗菌开发和光化学应用方面的潜力。
