Dave Sahil, Khokhar Suhirad, Mahmud Waqas, Alshal Mohamed, Diks John
Pathology, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.
Orthopedics, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.
Cureus. 2025 Jul 31;17(7):e89165. doi: 10.7759/cureus.89165. eCollection 2025 Jul.
A 53-year-old right-hand-dominant man presented with a recurrent, painful mass localized to the volar surface of the right small finger, leading to discomfort and impaired function. Radiographic imaging was unremarkable for osseous involvement. Surgical excision followed by histopathological and immunohistochemical (IHC) analysis established the diagnosis of angioleiomyoma, marked by desmin-positive smooth muscle fibers and CD34-positive vasculature. Given its infrequency in the hand and overlap with more common benign lesions, angioleiomyoma remains diagnostically elusive. This report emphasizes the pivotal role of tissue-based diagnostics and supports excision as a definitive treatment modality.
一名53岁惯用右手的男性患者，其右手小指掌侧出现一个复发性疼痛性肿块，导致不适和功能受损。影像学检查未发现骨受累情况。手术切除后进行组织病理学和免疫组织化学（IHC）分析，确诊为血管平滑肌瘤，其特征为结蛋白阳性的平滑肌纤维和CD34阳性的脉管系统。鉴于血管平滑肌瘤在手部罕见且与更常见的良性病变有重叠，其诊断仍具有挑战性。本报告强调了基于组织的诊断的关键作用，并支持将切除作为一种确定性的治疗方式。
