Zisis Vasileios, Charisi Christina, Poulopoulos Konstantinos, Papadopoulos Petros, Poulopoulos Athanasios
Department of Oral Medicine/Pathology 1, School of Dentistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Reports (MDPI). 2025 Feb 8;8(1):19. doi: 10.3390/reports8010019.
: Lipomas, benign tumors composed of adipose tissue, are recognized as one of the two most common fat-containing soft tissue tumors, underscoring their relative prevalence among benign tumors in children. Despite their prominence, lipomas rarely occur before 20 years of age, highlighting a discrepancy between their commonality and the age at which they typically manifest. This case report focuses on a 11-year-old patient who noticed the presence of an intraoral mass, which prompted further investigation, ultimately leading to the diagnosis of a lipoma located on the palate. Following our diagnosis, we searched for similar cases; however, the relevant literature was rather limited. There was a case report of a 4-year-old patient who presented with a lipoma on her tongue and a case report of a 6-year-old patient who presented with a lipoma on the buccal mucosa. The young patient came with his parents to the Department of Oral Medicine and Pathology, School of Dentistry, Aristotle University of Thessaloniki, Greece, and reported the presence of a growth in the middle of the upper jaw. A tumor, of approximately 1 cm diameter, was observed in the middle of the palate, on the border between the hard and soft palate. The surrounding mucosa appeared normal, which is critical in differentiating the tumor from more aggressive pathological entities. It was characterized by a soft and slippery consistency. The patient was referred to a cone beam computed tomography (CBCT) examination to investigate if there was any bone involvement. Based on clinical and radiographical findings, a biopsy was carried out. The tumor was initially excised in its entirety and the base was electrocauterized to avoid placing sutures. The histopathological examination that followed suggested the presence of an intraoral lipoma since lobules of mature adipose tissue in lamina propria and fatty tissue in close proximity to mucinous salivary glands were noticed. The development of lipomas in young patients can be attributed to a multitude of factors that interplay with one another, emphasizing the need for a comprehensive understanding of these growths. Additionally, underlying conditions such as diabetes mellitus, hypercholesterolemia, and obesity also play a crucial role, highlighting the interconnected nature of metabolic disorders and lipoma formation. The surgical approaches for the removal of oral lipomas primarily revolve around complete surgical excision, which is considered the mainstay treatment for these benign tumors.
脂肪瘤是由脂肪组织构成的良性肿瘤,被认为是两种最常见的含脂肪软组织肿瘤之一,这突出了它们在儿童良性肿瘤中的相对患病率。尽管脂肪瘤较为常见,但很少在20岁之前出现,这凸显了其普遍性与典型发病年龄之间的差异。本病例报告聚焦于一名11岁患者,该患者发现口腔内有肿物,遂进行进一步检查,最终诊断为位于腭部的脂肪瘤。确诊后,我们检索了类似病例;然而,相关文献相当有限。有一例4岁患者舌部出现脂肪瘤的病例报告,以及一例6岁患者颊黏膜出现脂肪瘤的病例报告。该年轻患者随父母前往希腊塞萨洛尼基亚里士多德大学牙科学院口腔医学与病理学系,报告上颌中部有肿物生长。在硬腭和软腭交界处的腭中部观察到一个直径约1厘米的肿瘤。周围黏膜外观正常,这对于将该肿瘤与更具侵袭性的病理实体区分开来至关重要。其特征为质地柔软且光滑。患者被转诊进行锥形束计算机断层扫描(CBCT)检查,以探究是否有骨受累情况。基于临床和影像学检查结果,进行了活检。肿瘤最初被完整切除,其基底进行了电灼以避免缝合。随后的组织病理学检查显示存在口腔脂肪瘤,因为在固有层中发现了成熟脂肪组织小叶以及紧邻黏液性唾液腺的脂肪组织。年轻患者脂肪瘤的发生可归因于多种相互作用的因素,这强调了全面了解这些肿瘤生长情况的必要性。此外,诸如糖尿病、高胆固醇血症和肥胖等潜在疾病也起着关键作用,凸显了代谢紊乱与脂肪瘤形成之间的内在联系。口腔脂肪瘤的手术切除方法主要围绕完全手术切除展开,这被认为是这些良性肿瘤的主要治疗方法。