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儿童原发性肺转移的低分化侵袭性骶骨脊索瘤——病例报告

Poorly Differentiated Aggressive Sacral Chordoma With Upfront Lung Metastases in a Child-A Case Report.

作者信息

Dokania Shubham, Nanda Sambit S, Patne Shashikant C U, Azad Shabana, Sisodiya Rahul, Mukherji Ashutosh

机构信息

Department of Radiation Oncology Homi Bhabha Cancer Hospital, Homi Bhabha National Institue Varanasi India.

Department of Oncopathology Homi Bhabha Cancer Hospital, Homi Bhabha National Institue Varanasi India.

出版信息

Clin Case Rep. 2025 Aug 1;13(8):e70738. doi: 10.1002/ccr3.70738. eCollection 2025 Aug.

Abstract

Poorly differentiated chordoma is a very unique type of chordoma with a particularly aggressive clinical course and high metastatic potential. It almost exclusively affects children and young adolescents. Unlike conventional chordomas, poorly differentiated chordomas cannot be well controlled with surgery and radiation therapy. Systemic agents are required for the treatment of this aggressive malignancy.

摘要

低分化脊索瘤是一种非常独特的脊索瘤类型,具有特别侵袭性的临床病程和高转移潜能。它几乎只影响儿童和青少年。与传统脊索瘤不同,低分化脊索瘤无法通过手术和放射治疗得到良好控制。治疗这种侵袭性恶性肿瘤需要全身用药。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afcf/12317115/8cecac1c7861/CCR3-13-e70738-g003.jpg

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