Dahiya Ekta, Lowe Andrew, Krishnamurthi Rita, Anand Gautam, Kalra Anubha
Institute of Biomedical Technologies (IBTec), Auckland University of Technology, Auckland, New Zealand.
National Institute of Stroke and Applied Neurosciences (NISAN), Auckland University of Technology, Auckland, New Zealand.
J R Soc N Z. 2025 Jun 23;55(6):2198-2215. doi: 10.1080/03036758.2025.2520388. eCollection 2025.
This study aimed to establish normal and reference pulse wave velocity (PWV) values and assess their relationship with the established cardiovascular risk factors in NZ. An observational cross-sectional study of 120 adults above 18 years was conducted at Auckland University of Technology within three age groups (18-30, 31-60, and >60 years) and four blood pressure (BP) categories (normal, elevated, stage 1 and stage 2) before being clustered as Normal Value Population (NVP) and Reference Value Population (RVP) based on BP and presence of other CVD risk. PWV was measured using Doppler ultrasound via the direct carotid-femoral method (distance × 0.8). Mean PWV for the whole study population was 5.88 ± 1.49 m/s and increased with age ( < 0.001) and with a more profound rise in the RVP group ( < 0.001, z = -4.98). Overall PWV values were lower than international reference standards, which may reflect population-specific physiological or methodological factors. A significant difference in mean PWV in the European and non-European populations ( = 0.004) indicated that ethnicity was an important part of the assessment. Age and mean blood pressure were the strongest predictors of PWV, accounting for 54.5% of the variability.
本研究旨在确定正常和参考脉搏波速度(PWV)值,并评估其与新西兰既定心血管危险因素的关系。在奥克兰理工大学对120名18岁以上的成年人进行了一项观察性横断面研究,研究对象分为三个年龄组(18 - 30岁、31 - 60岁和>60岁)和四个血压(BP)类别(正常、升高、1期和2期),然后根据血压和其他心血管疾病风险的存在情况分为正常值人群(NVP)和参考值人群(RVP)。使用多普勒超声通过直接颈股动脉法(距离×0.8)测量PWV。整个研究人群的平均PWV为5.88±1.49米/秒,且随年龄增加而升高(<0.001),在RVP组中升高更为显著(<0.001,z = -4.98)。总体PWV值低于国际参考标准,这可能反映了特定人群的生理或方法学因素。欧洲和非欧洲人群的平均PWV存在显著差异(= 0.004),表明种族是评估的重要组成部分。年龄和平均血压是PWV的最强预测因素,占变异性的54.5%。
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